Detection of Plasmid Borne Extended Spectrum Beta Lactamase Enzymes from Blood and Urine Isolates of Gram-Negative Bacteria from a University Teaching Hospital in Nigeria

Antibiotic Susceptibility Pattern of Extended Spectrum Betalactamase (ESBL) Producers and other Bacterial Pathogens in Kano, Nigeria

“…The prevalence of ESBL producers in this study was 12.8 %, which is higher than an earlier study in Kano [14] that reported 9.25 %, but much lower than a report of 36.2 % from Ebonyi State in Nigeria [15]. However, these results are higher than the report of 2.6 % from researchers in Bosnia and Herzegovina [16], and also 8.9 % from Saudi Arabia [17].…”

Antibiogram and plasmid profiling of carbapenemase and extended spectrum Beta-lactamase (ESBL) producing <I>Escherichia coli</I> and <I>Klebsiella pneumoniae</I> in Abeokuta, South western, Nigeria

“…It is lower than a similar report from the same study environment which reported a rate of 27.3% ESBL prevalence among enteric isolates 3 . Our results are also far lower than the report of Iroha et al 19 which reported a prevalence of 56.6% ESBL production in Klebsiella spp. isolates from blood and urine in ESUTH Enugu Southeastern Nigeria.…”

“…isolates from blood and urine in ESUTH Enugu Southeastern Nigeria. Iroha et al 19 also reported a 59.4% ESBL production in E. coli isolates from blood and urine in ESUTH Enugu Southeastern Nigeria. This shows the extent of epidemic spread the ESBL resistance phenotype is taking particularly in Southern Nigerian Hospital settings.…”

Beta-lactamase production by bacteria isolated from the gastrointestinal, urogenital and urinary tracts of patients at Murtala Muhammed specialist hospital and decent laboratory, Kano

“…28(13.15%) for urine specimen and E. coli 30(14.08%) and Klebsiella spp 3(1.41%) for stool specimen. This is similar to recent study conducted in Nsukka metropolis by Eze et al, (2015), in which distribution of β-lactamase was determined among clinical specmens and urine had the highest prevalence of 86.7% followed by stool with prevalence of 84.6%, this study is also in agreement with a report by Doughari and Akafa (2009) who reported a prevalence rate of 91% of β-lactamase enzyme from bacterial isolates from urine specimen and Iroha et al, (2010) who reported 60.3% of of β-lactamase in urine specimen. The high prevalence of β-lactamase in urine clinical isolates may be attributed factors like extreme age, sexual activity, contraception, pregancy, urinary tract obstruction, neurological dysfunction, antimicrobial use and poor hand washing techniques among health care practitioners as reported by Eze et al, (2015).…”