Detection of Premature Ventricular Contractions on a Ventricular Electrocardiogram for Patients With Left Ventricular Assist Devices

Park, Sung Min; Lee, Jun Young; Choi, Seung Wook

doi:10.1111/aor.12306

Cited by 5 publications

(4 citation statements)

References 34 publications

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“…Here, the average VAD inflow can be calculated from VAD operating conditions [ 19 ]. The total average flow can be measured by subtracting the inflow to the VAD from the flow measured by thermodilution.…”

Section: Methodsmentioning

confidence: 99%

“…The inlet and outlet cannulas of the LVAD (LibraHeart I; LibraHeart Inc., Chuncheon, Korea) were connected to the animal’s LV and aorta, respectively, and the other ends of the cannulas were connected to the inlet and outlet ports of the pump for use as a pulsatile LVAD [ 15 , 19 ]. The v-ECGs were measured using electrodes set on the surfaces of the inlet and outlet cannulas; the electrodes were in contact with the heart muscle and aorta wall when the cannulas were connected [ 15 , 16 , 19 ]. v-ECG measurement on the LV is similar to a unipolar-lead ECG measurement, except that the electrode contacts the cardiac muscle directly; the measurable range is limited, and the pattern of waveforms is very simple.…”

Section: Methodsmentioning

confidence: 99%

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Heart monitoring using left ventricle impedance and ventricular electrocardiography in left ventricular assist device patients

et al. 2015

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BackgroundPatients who develop critical arrhythmia during left ventricular assist device (LVAD) perfusion have a low survival rate. For diagnosis of unexpected heart abnormalities, new heart-monitoring methods are required for patients supported by LVAD perfusion. Ventricular electrocardiography using electrodes implanted in the ventricle to detect heart contractions is unsuitable if the heart is abnormal. Left ventricular impedance (LVI) is useful for monitoring heart movement but does not show abnormal action potential in the heart muscle.ObjectivesTo detect detailed abnormal heart conditions, we obtained ventricular electrocardiograms (v-ECGs) and LVI simultaneously in porcine models connected to LVADs.MethodsIn the porcine models, electrodes were set on the heart apex and ascending aorta for real-time measurements of v-ECGs and LVI. As the carrier current frequency of the LVI was adjusted to 30 kHz, it was easily derived from the original v-ECG signal by using a high-pass filter (cutoff: 10 kHz). In addition, v-ECGs with a frequency band of 0.1 – 120 Hz were easily derived using a low-pass filter. Simultaneous v-ECG and LVI data were compared to detect heart volume changes during the Q-T period when the heart contracted. A new real-time algorithm for comparison of v-ECGs and LVI determined whether the porcine heartbeats were normal or abnormal. Several abnormal heartbeats were detected using the LVADs operating in asynchronous mode, most of which were premature ventricle contractions (PVCs). To evaluate the accuracy of the new method, the results obtained were compared to normal ECG data and cardiac output measured simultaneously using commercial devices.ResultsThe new method provided more accurate detection of abnormal heart movements. This method can be used for various heart diseases, even those in which the cardiac output is heavily affected by LVAD operation.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Heart monitoring using left ventricle impedance and ventricular electrocardiography in left ventricular assist device patients

et al. 2015

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“…Sung Min Park et al. of the Kangwon National University, Chuncheon, Korea, compared the ventricular ECGs (v‐ECGs) of normal and abnormal heartbeats with respect to peak‐to‐peak voltage, area, and maximal slopes, and a new method to detect abnormal heartbeats was suggested. In animal experiments with three porcine models, a v‐ECG and conventional ECG were taken simultaneously during LVAD perfusion.…”

Section: Cardiac Support and Blood Pumpsmentioning

confidence: 99%

Artificial Organs 2014: A Year in Review

Malchesky¹

2015

Artificial Organs

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In this Editor's Review, articles published in 2014 are organized by category and briefly summarized. We aim to provide a brief reflection of the currently available worldwide knowledge that is intended to advance and better human life while providing insight for continued application of technologies and methods of organ Replacement, Recovery, and Regeneration. As the official journal of the International Federation for Artificial Organs, the International Faculty for Artificial Organs, the International Society for Rotary Blood Pumps, the International Society for Pediatric Mechanical Cardiopulmonary Support, and the Vienna International Workshop on Functional Electrical Stimulation, Artificial Organs continues in the original mission of its founders "to foster communications in the field of artificial organs on an international level." Artificial Organs continues to publish developments and clinical applications of artificial organ technologies in this broad and expanding field of organ Replacement, Recovery, and Regeneration from all over the world. We take this time also to express our gratitude to our authors for offering their work to this journal. We offer our very special thanks to our reviewers who give so generously of time and expertise to review, critique, and especially provide meaningful suggestions to the author's work whether eventually accepted or rejected. Without these excellent and dedicated reviewers, the quality expected from such a journal could not be possible. We also express our special thanks to our Publisher, John Wiley & Sons, for their expert attention and support in the production and marketing of Artificial Organs. We look forward to reporting further advances in the coming years.

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“…However, such systems are cumbersome and would require patients to carry additional cables and instrumentation. Previous studies suggested the possibility of measuring electrogram from the heart or the great vessels and using it as a control input to trigger an assist device [21][22][23][24]. This approach was initially used in patients for intra-aortic balloon pumps [25].…”

Section: Introductionmentioning

confidence: 99%

Synchronization of a Soft Robotic Ventricular Assist Device to the Native Cardiac Rhythm Using an Epicardial Electrogram

Bautista‐Salinas

Hammer

Wamala

et al. 2020

Journal of Medical Devices

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Soft robotic devices have been proposed as an alternative solution for ventricular assistance. Unlike conventional ventricular assist devices (VADs) that pump blood through an artificial lumen, soft robotic VADs (SRVADs) use pneumatic artificial muscles (PAM) to assist native contraction and relaxation of the ventricle. Synchronization of SRVADs is critical to ensure maximized and physiologic cardiac output. We developed a proof-of-concept synchronization algorithm that uses an epicardial electrogram as an input signal and evaluated the approach on adult Yorkshire pigs (n = 2). An SRVAD previously developed by our group was implanted on the right ventricle (RV). We demonstrated an improvement in the synchronization of the SRVAD using an epicardial electrogram signal versus a RV pressure signal of 4 ± 0.5% in heart failure and 3.2 ± 0.5% during actuation for animal 1 and 7.4 ± 0.6% in heart failure and 8.2% ± 0.8% during actuation for animal 2. Results suggest that improved synchronization is translated in greater cardiac output. The pulmonary artery (PA) flow was restored to a 107% and 106% of the healthy baseline during RV electrogram actuation and RV pressure actuation, respectively, in animal 1, and to a 100% and 87% in animal 2. Therefore, the presented system using the RV electrogram signal as a control input has shown to be superior in comparison with the use of the RV pressure signal.

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Detection of Premature Ventricular Contractions on a Ventricular Electrocardiogram for Patients With Left Ventricular Assist Devices

Cited by 5 publications

References 34 publications

Heart monitoring using left ventricle impedance and ventricular electrocardiography in left ventricular assist device patients

Heart monitoring using left ventricle impedance and ventricular electrocardiography in left ventricular assist device patients

Artificial Organs 2014: A Year in Review

Synchronization of a Soft Robotic Ventricular Assist Device to the Native Cardiac Rhythm Using an Epicardial Electrogram

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