Detection of the 23-bp nucleotide sequence mutation in retinoid acid receptor related orphan receptor alpha <i>(RORA)</i> gene and its effect on sheep litter size

Yang, Yifan; Hu, Huina; Mao, Chenchen; Jiang, Fugui; Lu, Xiufen; Han, Xufei; Hao, Kunjie; Lan, Xianyong; Zhang, Qingfeng; Pan, Chuanying

doi:10.1080/10495398.2020.1770273

Cited by 8 publications

(6 citation statements)

References 38 publications

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“…The topic difference between different regions once again proves the necessity of comparative studies on the same subject under different cultural backgrounds. One salient problem is that many existing empirical studies imitated the previous research models in the new context and did not produce substantive theoretical contributions or progress (Utkarsh and Sigala, 2021; Yang et al , 2022), such as the variety of studies surrounding the negative impact of risk perception on travel intentions and behavior (Bae and Chang, 2021; Sánchez-Cañizares et al , 2021). This research finally identifies future research directions based on a three-dimensional framework.…”

Section: Discussionmentioning

confidence: 99%

“…According to a comparative review by Ritchie and Jiang (2021), research on disaster, crisis and risk in the generic field usually focuses on three themes: communication, management and reduction, and most of the crisis studies in the tourism and hospitality industry focus on the response and recovery stages, which draw on the concept of strategic management (Jiang et al , 2019). The COVID-19 pandemic is not only an industry crisis but also a global disaster (Yang et al , 2022). However, previous studies on tourism and disease are usually synchronized with the instantaneity of diseases, and the theoretical basis of the research theme is also weak (Chen et al , 2021).…”

Section: Literature Reviewmentioning

confidence: 99%

“…The continuous development of this literature flow has prompted some scholars to review and reflect on it. Existing studies (Utkarsh and Sigala, 2021; Yang et al , 2022; Zenker and Kock, 2020; Zopiatis et al , 2021) reviewing COVID-19-related research in hospitality and tourism have focused on systematically reviewing research themes to develop future research directions. These papers provide some insights to understand the impact of the COVID-19 pandemic on tourism, but they also contain flaws.…”

Section: Literature Reviewmentioning

confidence: 99%

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Research progress and future agenda of COVID-19 in tourism and hospitality: a timely bibliometric review

Liu

Zhou

et al. 2022

IJCHM

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Purpose A proliferation of articles surrounding the COVID-19 pandemic is calling for new insights through review. This paper aims to bibliometrically analyze the current progress of research around hospitality and tourism to define the research directions on herd immunity and the prevention of disease under the “new normal.” Design/methodology/approach This paper analyzed 326 articles regarding COVID-19 published in SSCI hospitality, leisure and tourism journals in 2020 and 2021 by combining manual analysis and bibliometrics to reveal research topics and to gain insight into research structures. Findings The results of this paper summarized topics related to stakeholders’ mentality and behavior, responses of travel suppliers to the COVID-19 pandemic, economic impact and demand forecasting, social issues of human rights and racism and reflection on tourism and transformation of the industry. More research is called for in the future to focus on a better response to the crisis, including crisis management education and training and the improving the resilience of small- and medium-sized enterprises. Research limitations/implications A three-dimensional consideration was proposed to promote the sustainable development of hospitality and tourism. Originality/value In the “new normal” phase of herd immunity and disease prevention, to the best of the authors’ knowledge, this is the first paper that provides an up-to-date systematic overview of the evolution of COVID-19 research in tourism and hospitality and encourages more conceptual, practical and futuristic studies.

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Section: Discussionmentioning

confidence: 99%

Section: Literature Reviewmentioning

confidence: 99%

Section: Literature Reviewmentioning

confidence: 99%

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Research progress and future agenda of COVID-19 in tourism and hospitality: a timely bibliometric review

Liu

Zhou

et al. 2022

IJCHM

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“…Haplotype frequencies and different genotype combinations of the two InDels were significant in goats. Besides, the PIC of P2-Del-20bp exhibited low polymorphism and the PIC of P1-Del-17bp showed medium polymorphism, indicating that their solid potential value for selection in goat breeds ( 40 ). Moreover, these variants did not conform to HWE.…”

Section: Discussionmentioning

confidence: 99%

Goat SNX29: mRNA expression, InDel and CNV detection, and their associations with litter size

Wang

et al. 2022

Front. Vet. Sci.

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The sorting nexin 29 (SNX29) gene, a member of the SNX family, is associated with material transport and lipid metabolism. Previous studies have shown that lipid metabolism affects reproductive function in animals. Thus, we hypothesized there is a correlation between the SNX29 gene and reproductive trait. To date, studies on the relationship between the SNX29 gene and reproductive traits are limited. Therefore, the purpose of this study was to examine the polymorphism in the SNX29 gene and its correlation with litter size. Herein, the mRNA expression levels of SNX29 were assayed in various goat tissue. Surprisingly, we found that SNX29 was highly expressed in the corpus luteum, large and small follicles. This result led us to suggest that the SNX29 gene has a critical role in reproduction. We further detected potential polymorphisms in Shaanbei white cashmere (SBWC) goats, including insertion/deletion (InDel, n = 2,057) and copy number variation (CNV, n = 1,402), which were related to fertility. The 17 bp deletion (n = 1004) and the 20 bp deletion (n = 1,053) within the SNX29 gene were discovered to be significantly associated with litter size (P < 0.05), and individuals the ID genotype of P1-Del-17 bp and the DD genotype of P2-Del-20bp had larger litter size. Additionally, the four CNV loci had significant correlations with litter size (P < 0.01) in our detected population. In CNV5, individuals with the median genotype were superior compared to those with loss or gain genotype in term of litter size, and in other three CNVs showed better reproductive trait in the gain genotype. Briefly, these findings suggest that SNX29 could be used as a candidate gene for litter size in goat breeding through marker-assisted selection (MAS).

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“…The association between the variants and growth traits was explored using the analysis of variance (ANOVA) and independent sample t -test in SPSS 26.0 (IBM, USA), and the chi-square (χ 2 ) test was used to analyze the significance between the three breeds ( 32 ). And the line model was used as a reference by Liu et al ( 33 ).…”

Section: Methodsmentioning

confidence: 99%

Detection distribution of CNVs of SNX29 in three goat breeds and their associations with growth traits

Wang,

Song,

et al. 2023

Front. Vet. Sci.

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As a member of the SNX family, the goat sorting nexin 29 (SNX29) is initially identified as a myogenesis gene. Therefore, this study aimed to examine the polymorphism in the SNX29 gene and its association with growth traits. In this study, we used an online platform to predict the structures of the SNX29 protein and used quantitative real-time PCR to detect potential copy number variation (CNV) in Shaanbei white cashmere (SBWC) goats (n = 541), Guizhou black (GB) goats (n = 48), and Nubian (NB) goats (n = 39). The results showed that goat SNX29 protein belonged to non-secretory protein. Then, five CNVs were detected, and their association with growth traits was analyzed. In SBWC goats, CNV1, CNV3, CNV4, and CNV5 were associated with chest width and body length (P < 0.05). Among them, the CNV1 individuals with gain and loss genotypes were superior to those individuals with a median genotype, but CNV4 and CNV5 of individuals with the median genotype were superior to those with the loss and gain genotypes. In addition, individuals with the gain genotype had superior growth traits in CNV3. In brief, this study suggests that the CNV of SNX29 can be used as a molecular marker in goat breeding.

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Detection of the 23-bp nucleotide sequence mutation in retinoid acid receptor related orphan receptor alpha (RORA) gene and its effect on sheep litter size

Cited by 8 publications

References 38 publications

Research progress and future agenda of COVID-19 in tourism and hospitality: a timely bibliometric review

Research progress and future agenda of COVID-19 in tourism and hospitality: a timely bibliometric review

Goat SNX29: mRNA expression, InDel and CNV detection, and their associations with litter size

Detection distribution of CNVs of SNX29 in three goat breeds and their associations with growth traits

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