Detection of two CSN1S1 variants in Egyptian buffalo

Nahas, Soheir M. El; Bibars, Mona A.; Taha, Dalia A.; El‐Sayyad, Hassan I.

doi:10.1016/j.jgeb.2013.01.001

Cited by 5 publications

(2 citation statements)

References 8 publications

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“…The characteristics of milk are controlled by several genes, in particular, the four casein genes, CSN1S1, CSN1S2, CSN2, and CSN3, which are responsible for encoding the four fractions of the protein α-casein -α-casein s1, α-casein s2, β-casein and κ-casein (El Nahas et al 2013).…”

Section: Introductionmentioning

confidence: 99%

“…The CSN1S1 gene is located on chromosome 7 and is formed by 19 exons (NCBI-Gene ID 102396531-). Most studies that investigated the polymorphism of this gene involved the exons 17 and 19 (El Nahas et al 2013). However, the studies have only found polymorphisms in the promoter region of this gene, as this region is fundamental for the transcription of the gene (Alves & Souza 2013).…”

Section: Introductionmentioning

confidence: 99%

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CSN1S1 and CSN3 gene variants in female Murrah buffaloes in the Brazilian Amazon

Medeiros

Guerreiro

Pereira

et al. 2022

An. Acad. Bras. Ciênc.

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The characteristics of milk are controlled by several genes, with emphasis on the four genes from casein, CSN1S1; CSN1S2; CSN2 and CSN3, which are responsible encoding of fractions the milk protein. The study of genetic variants in these genes, seek to investigate alleles, insertions or deletions, that can directly refl ect on productive characteristics, indicating differences in milk quality, composition and yield. The CSN1S1 and CSN3 genes were analyzed in lactating Murrah buffaloes using nucleotide sequencing. An SNP was found in the amplifi ed fragment of the CSN1S1 gene, located in nucleotide number 2,123 of the promoter region in position nt-258 (A/G). As for the CSN3 gene, two SNPs of exon number 4 were identifi ed in codons 33 (ACC/ATC) and 34 (ACC/ ACT) of the analyzed fragment. This study contributes to important associations between genetic variants and the desired characteristics of milk and its derivatives in future studies, because the variants found may be associated with the quality of milk, enabling genetic selection to be assisted by molecular markers, indicating a major advance that makes it possible to select animals early.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

CSN1S1 and CSN3 gene variants in female Murrah buffaloes in the Brazilian Amazon

Medeiros

Guerreiro

Pereira

et al. 2022

An. Acad. Bras. Ciênc.

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DNA polymorphisms of FGFBP1, leptin, κ-casein, and αs1-casein genes and their association with reproductive performance in dromedary she-camels

et al. 2022

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Nutritional and therapeutic significance of non-bovine milk for human health applications

Verma

Rout

2022

CABI Reviews

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Non-bovine milk(s) and their dairy products are showing a rise in market demand as they are gaining consumers’ attention. Non-bovine milk serves as an important source of nutrition and sustenance for populations in difficult climatic and geographical regions. Milk from different non-bovine species is known to have several nutritional and therapeutic values. Thus, it becomes important to study the composition and constituents of non-bovine milk(s) and their products with respect to microbial load and post-translational modifications of proteins in human health applications. The cheeses and fermented milk products produced from non-bovine milk are widely distributed across a large variety of climatic and geographical areas. Non-bovine milk proteomics is being analysed to know the role of milk proteins and peptides in metabolism, immune regulation and disease pathways for application in nutraceutical and drug development. Therapeutic proteins for human use are being produced in the “goat model” as a bio-reactor. The biological potential of milk is manifold as it is transformed into various products with specific nutritive and health-promoting values. Therefore, the purpose of this article is to review different aspects of non-bovine milk(s) in nutrition, traditional dairy product, milk proteome, bioactive peptides, microbiota and antimicrobial resistance due to intensive production for diverse applications and better economic impact in different regions.

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Detection of two CSN1S1 variants in Egyptian buffalo

Cited by 5 publications

References 8 publications

CSN1S1 and CSN3 gene variants in female Murrah buffaloes in the Brazilian Amazon

CSN1S1 and CSN3 gene variants in female Murrah buffaloes in the Brazilian Amazon

DNA polymorphisms of FGFBP1, leptin, κ-casein, and αs1-casein genes and their association with reproductive performance in dromedary she-camels

Nutritional and therapeutic significance of non-bovine milk for human health applications

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