“…Only a few of the mentioned studies [7,19,27,35,39,40] use real ECG recordings with erroneous electrode placements, which are, however, small-sized and proprietary. Typically, reversal detection algorithms are trained and validated using databases with correctly recorded 12-lead ECGs and simulated reversals within the limb lead set [11,26,28,29,30,31,32,33,34,36,38] or the precordial lead set [11,26,31,33,34,38], where the Wilson’s central terminal (WCT) is not changed. All other reversals modifying the WCT, such as swaps between the limb and precordial electrodes, have not been simulated, although they are quite possible and should be detected due to the distorted morphology of most leads [6,8,21].…”