Detectors for medical radioisotope imaging: demands and perspectives

Lopes, I.; Chepel, V.

doi:10.1016/j.radphyschem.2004.04.058

Cited by 6 publications

(10 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this way, by using the attenuation coefficient of the LYSO and the exponential attenuation law, the boundaries of the 4 depth of interaction intervals were obtained, the thickness of the intervals increase with depth in the crystal. Considering an attenuation length of the scintillator of 12 mm (Lopes et al 2004), the four DOIs corresponded to the intervals [0 mm, 1.83 mm], [1.83 mm, 3.99 mm], [3.99 mm, 6.62 mm] and [6.62 mm, 10 mm] (assuming a value of DOI = 0 mm at the entrance of the scintillator). Four Depth of Interaction intervals were chosen according to the results obtained in DOI resolution with the cMiCE detector in (Ling et al 2007).…”

Section: Methodsmentioning

confidence: 99%

Evaluation of event position reconstruction in monolithic crystals that are optically coupled

et al. 2016

View full text Add to dashboard Cite

A PET detector featuring a pseudo-monolithic crystal is being developed as a more cost-effective alternative to a full monolithic crystal PET detector . This work evaluates different methods to localize the scintillation events in quartered monolithic crystals that are optically coupled. A semi-monolithic crystal assembly was formed using four 26 × 26 × 10 mm3 LYSO crystals optically coupled together using optical adhesive, to mimic a 52 × 52 × 10 mm3 monolithic crystal detector. The crystal assembly was coupled to a 64-channel multi-anode photomultiplier tube using silicon grease. The detector was calibrated using a 34 × 34 scan grid. Events were first filtered and depth separated using a multi-Lorentzian fit to the collected light distribution. Next, three different techniques were explored to generate the look up tables for the event positioning. The first technique was 'standard interpolation' across the interface. The second technique was 'central extrapolation', where a bin was placed at the midpoint of the interface and events positioned within the interface region were discarded. The third technique used a 'central overlap' method where an extended region was extrapolated at each interface. Events were then positioned using least-squares minimization and maximum likelihood methods. The least-squares minimization applied to the look up table generated with the standard interpolation technique had the best full width at half maximum (FWHM) intrinsic spatial resolution and the lowest bias. However, there were discontinuities in the event positioning that would most likely lead to artifacts in the reconstructed image. The central extrapolation technique also had discontinuities and a 30% sensitivity loss near the crystal-crystal interfaces. The central overlap technique had slightly degraded performance metrics, but it still provided ~2.1 mm intrinsic spatial resolution at the crystal-crystal interface and had a symmetric and continuously varying response function. Results using maximum likelihood positioning were similar to least-squares minimization for the central overlap data.

show abstract

Section: Methodsmentioning

confidence: 99%

Evaluation of event position reconstruction in monolithic crystals that are optically coupled

et al. 2016

View full text Add to dashboard Cite

show abstract

“…[292735] Having a high intrinsic sensitivity reduces the detector thickness for obtaining suitable sensitivity and subsequently improves the spatial resolution. [27] Park et al .…”

Section: Cadmium Telluride Detectormentioning

confidence: 99%

“…Conventional SPECT system is mostly based on NaI(Tl) as main component of photon interaction, with a high luminous efficiency, and is costly effective. [ 1 5 9 ] However, it has some limitations such as low-energy resolution, low intrinsic spatial resolution, and hygroscopic. [ 5 10 11 ] The low intrinsic spatial resolution is confined by its low density (3.76 g/cm 3 )[ 10 12 13 14 ] and low-energy resolution related to the abundant PMTs needed for the positioning circuit.…”

Section: Introductionmentioning

confidence: 99%

Cadmium telluride semiconductor detector for improved spatial and energy resolution radioisotopic imaging

2017

View full text Add to dashboard Cite

The detector in single-photon emission computed tomography has played a key role in the quality of the images. Over the past few decades, developments in semiconductor detector technology provided an appropriate substitution for scintillation detectors in terms of high sensitivity, better energy resolution, and also high spatial resolution. One of the considered detectors is cadmium telluride (CdTe). The purpose of this paper is to review the CdTe semiconductor detector used in preclinical studies, small organ and small animal imaging, also research in nuclear medicine and other medical imaging modalities by a complete inspect on the material characteristics, irradiation principles, applications, and epitaxial growth method.

show abstract

“…The two primary diagnostic imaging methods are single photon imaging and positron emission tomography (PET) (29). The two primary diagnostic imaging methods are single photon imaging and positron emission tomography (PET) (29).…”

mentioning

confidence: 99%

“…Nuclear medicine (NM) uses radiotracers to diagnose and treat disease and in many countries is a subspecialty of radiology. The two primary diagnostic imaging methods are single photon imaging and positron emission tomography (PET) (29).…”

mentioning

confidence: 99%

The effects of technological developments on nuclear medicine technologist productivity: A systematic review

Adams

Cox

Schofield

et al. 2009

Int J Technol Assess Health Care

View full text Add to dashboard Cite

show abstract

Detectors for medical radioisotope imaging: demands and perspectives

Cited by 6 publications

References 43 publications

Evaluation of event position reconstruction in monolithic crystals that are optically coupled

Evaluation of event position reconstruction in monolithic crystals that are optically coupled

Cadmium telluride semiconductor detector for improved spatial and energy resolution radioisotopic imaging

The effects of technological developments on nuclear medicine technologist productivity: A systematic review

Contact Info

Product

Resources

About