Detergent components in sewage effluent are weakly oestrogenic to fish: An in vitro study using rainbow trout (Oncorhynchus mykiss) hepatocytes

Decellularization of pericardial tissue and its impact on tensile viscoelasticity and glycosaminoglycan content

“…In addition, a highly negative charged pericardial tissue has been associated to a higher tendency to tissue calcification [34]. Due to these SDS disadvantages and considering the potential toxicity of non-ionic phenolic detergents [25][26][27], ATE plus alkaline treatments were used.…”

“…However, there are some issues related to the use of aromatic (phenolic) or non-aromatic (non-phenolic) non-ionic detergents used in the decellularization process. For example, the biodegradation products of derivatives of non-ionic detergents such as alkylphenol ethoxylates have been associated to toxicity [25] and estrogenic effects [26,27].…”

Monitoring of selected estrogenic compounds and estrogenic activity in surface water and sediment of the Yellow River in China using combined chemical and biological tools

“…The observed effects in fish include vitellogenin induction, abnormal development of gonads (Harries et al, 1997;Lye et al, 1997;Jobling et al, 2002) and secondary sexual characteristics (Batty and Lim, 1999;Xie et al, 2010), which have been linked to some estrogenic compounds in the effluents of sewage treatment plants (Harries et al, 1997;Jobling et al, 2002;Lye et al, 1997;Thorpe et al, 2003;Xie et al, 2010). These compounds include 4-t-octylphenol (4-t-OP), 4-nonylphenols (4-NP), bisphenol-A (BPA), estrone (E1), estradiol (E2) and triclosan (TCS), which have been demonstrated to have in vitro and/or in vivo estrogenic activities (Foran et al, 2000;Ishibahsi et al, 2004;Jobling and Sumpter, 1993;Jobling et al, 1995;Raut and Angus, 2010;Stasinakis et al, 2008). Therefore, it is essential to monitor these estrogenic compounds in aquatic environments in order to protect the ecosystem.…”

Determination of Bioavailable Contaminants in the Lower Missouri River following the Flood of 1993

“…It is subsequently released into the plasma from which it is removed by the ovary. Liver VTG production can be induced in immature female fish as well as male fish by injection of estradiol (30)(31)(32). There is also evidence that VTG production is induced in male fish that have been exposed to environmental contaminants (33,34).…”