Determinação de 25-hidroxivitamina D2 e D3 em plasma por CLAE-DAD

Kich, Daiana Manuele; Vieira, Fabiana Aparecida de Souza; Bassuino, Mauricio Sprenger; Linden, Rafael

doi:10.1590/s1676-24442012000500005

Cited by 4 publications

(1 citation statement)

References 19 publications

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“…Ergocalciferol is of vegetable origin, whereas cholecalciferol is of animal origin, being formed by ultraviolet B radiation on 7-dehydrocholesterol. 2 Vitamin D in these forms must be converted into active hormone to be able to exert biological influence on mineral metabolism and other physiological functions. 1 Physical activity is any movement of the body produced by skeletal muscles that results in greater energy expenditure than that of rest levels.…”

Section: Introductionmentioning

confidence: 99%

Association between physical activity and vitamin D: A narrative literature review

Fernandes

Barreto²

2017

Rev. Assoc. Med. Bras.

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This narrative review of the medical literature assessed whether outdoor and indoor physical activity would increase the plasma levels of vitamin D. Synthesis of this liposoluble vitamin is mainly mediated by sunlight on the skin, where it is activated to perform its main action, which is to control the serum levels of calcium as soon as the element is absorbed in the intestines, assisting in the regulation of bone metabolism. Physical activity is any body movement that results in energy expenditure, while outdoor physical activity refers to physical activity carried out at public parks or other open spaces, as is the case of the popular practice of taking walks. Exercising outdoors would have both the benefits of physical activity and of sun exposure, namely the synthesis of vitamin D. However, according to the studies analyzed, increased plasma concentration of vitamin D occurs with physical activity both indoors and outdoors.

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Section: Introductionmentioning

confidence: 99%

Association between physical activity and vitamin D: A narrative literature review

Fernandes

Barreto²

2017

Rev. Assoc. Med. Bras.

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Hypovitaminosis D and reduced cathelicidin are strongly correlated during the multidrug therapy against leprosy

Oliveira

Chaves

Cardoso

et al. 2020

Microbial Pathogenesis

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Free and Bioavailable Fractions of Vitamin D: Association with Maternal Characteristics in Brazilian Pregnant Women

Pereira

Chactoura

Nohra

et al. 2020

Journal of Nutrition and Metabolism

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Normal pregnancy is characterized by many changes in vitamin D metabolism, challenging the assessment of vitamin D status based exclusively on serum total 25-hydroxyvitamin D (25(OH)D). We hypothesized that measuring free and bioavailable fractions contributes to a better vitamin D status assessment in late pregnancy. Our aim was to evaluate a broad set of biomarkers of vitamin D status in Brazilian women in the third trimester of pregnancy. This cross-sectional study was conducted in women (n = 123, 18–44 y, 27–41 wk gestation) attended in a public maternity in Rio de Janeiro (2016–2018). Biomarkers included serum concentrations of total 25(OH)D3, parathyroid hormone (PTH), vitamin D-binding protein (DBP), and free and bioavailable fractions of 25(OH)D3. Vitamin D insufficiency (<50 nmol/L) was prevalent in 47.9% of the pregnant women. Serum 25(OH)D3 was inversely associated with the gestational week (β = −0.71, 95% confidence interval (CI): −1.31 to −0.16) and season, being lower in autumn (β = −9.90, 95% CI: −16.14 to -3.64) and winter (β = −16.74, 95%CI: −23.13 to −10.34). Concentrations of DBP, and free and bioavailable 25(OH)D3 were also inversely associated with winter months (P<0.05). DBP was directly associated with prepregnancy BMI (β = 5.84, 95% CI: 0.62 to 11.06). The recognized season-effect on total 25(OH)D3 appeared to also occur on free and bioavailable fractions. Although advanced gestational age was associated with lower total 25(OH)D3, our results suggest an adaptive mechanism responsible for maintaining free fraction during the 3rd trimester. We also suggest that starting pregnancy in obese condition may have an impact on vitamin D bioavailability, which deserves further investigation.

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Determinação de 25-hidroxivitamina D2 e D3 em plasma por CLAE-DAD

Abstract: Primeira submissão em 11/01/12 Última submissão em 11/01/12 Aceito para publicação em 16/07/12 Publicado em 20/10/12

Cited by 4 publications

References 19 publications

Association between physical activity and vitamin D: A narrative literature review

Association between physical activity and vitamin D: A narrative literature review

Hypovitaminosis D and reduced cathelicidin are strongly correlated during the multidrug therapy against leprosy

Free and Bioavailable Fractions of Vitamin D: Association with Maternal Characteristics in Brazilian Pregnant Women

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