Determinants of COVID-19 vaccine acceptance and hesitancy: a cross-sectional study in Saudi Arabia

Yahia, Amar Ibrahim Omer; Al-Shahrani, Abdullah M; Alsulmi, Wael Gabir H.; Alqarni, Mohammed Mesfer M.; Abdulrahim, Tamim Khalid Abdullah; Heba, Waleed Faya H; Alqarni, Turki; Alharthi, Khalid Ali Z; Buhran, Abdullah Ali A.

doi:10.1080/21645515.2021.1950506

Cited by 30 publications

(26 citation statements)

References 28 publications

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“…The present study showed that about 70% of the participants reported a moderate to high acceptance of the COVID-19 vaccine. Several other Saudi studies were almost in line with our results, which showed that 62-71% of Saudi citizens and Saudi residents have a good acceptance of COVID-19 vaccines (Narapureddy et al 2021;Alqahtani 2021;Alshahrani et al 2021;Maqsood et al 2022;Al-Mohaithef and Padhi 2020;Fadhel 2021;Yahia et al 2021;Elharake et al 2021). However, Khalafalla et al reported that 83.6% of Jazan University students were willing to take the COVID-19 vaccine, which was described as having a high acceptance rate compared to most studies conducted in Saudi Arabia (Khalafalla et al 2022).…”

Section: Discussionsupporting

confidence: 91%

COVID-19 vaccine acceptance: knowledge and beliefs

et al. 2022

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Backgrounds Vaccine acceptance varies across countries, generations, and the perceived personality of individuals. Investigating the knowledge, beliefs, and acceptability of COVID-19 vaccines among individuals is vital to ensuring adequate health system capacity and procedures and promoting the uptake of the vaccines. Results A cross-sectional study was conducted from August 2021 to January 2022 in Saudi Arabia. The study included 281 residents to estimate their acceptance to receive COVID-19 vaccination. Around 70% of the included participants had a moderate to high COVID-19 vaccine acceptance rate during the data collection period. The risk increases to about two folds among undergraduates [OR 1.846 (1.034–3.296), p value = 0.036)] and increases to four folds among non-employed [OR 3.944 (2.310–6.737), p value = 0.001]. About 78% of participants with high and 44% with low COVID-19 vaccine acceptance (p value = 0.001) believed the vaccines were safe and effective. The belief that COVID-19 disease will be controlled within two years increased the risk for low vaccine acceptance by about two folds [OR 1.730 (1.035–2.891), p value = 0.035]. Good knowledge about COVID-19 vaccination significantly affected the acceptance rate (p value = 0.001). Conclusions Several factors affect the intention of individuals to receive vaccines. Therefore, building good knowledge and health literacy through educational intervention programs, especially vaccine safety and effectiveness, is important for successful vaccination campaigns among the general population and ensuring control of the COVID-19 pandemic.

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Section: Discussionsupporting

confidence: 91%

COVID-19 vaccine acceptance: knowledge and beliefs

et al. 2022

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“…A descriptive analysis of the 531 participants showed that 61.8% were willing to get the COVID-19 vaccine, while 38.2% were not. COVID-19 vaccine hesitancy was more among women (44.9%), those 34-49 years of age (47.9%), those who were married (41.9%), employed (39.7%), had lower educational attainment (40%), and were urban dwellers (40.8%) [25].…”

Section: Discussionmentioning

confidence: 99%

COVID-19 Vaccination Willingness and Acceptability in Multiple Sclerosis Patients: A Cross Sectional Study in Iran

Nabavi

Mehrabani²,

Ghalichi

et al. 2022

Vaccines

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Multiple sclerosis (MS) is a chronic, predominantly immune-mediated degenerative disease of the central nervous system. Due to prolonged use of immunomodulatory and immunosuppressive medications, vaccine hesitancy could be common among MS patients. Our main aim in the current study was to evaluate the willingness and acceptability of COVID-19 vaccination in patients with MS. In our multicenter cross-sectional questionnaire-based clinical study, 892 patients completed the questionnaire between May to June 2021. The questionnaire consisted of demographic data, MS disease-related factors, history of COVID-19 infection/vaccination, and any existing comorbidities. Statistical analysis was performed using SPSS software version 19. Overall, 68% of the participants expressed willingness to be vaccinated. Major causes of vaccine refusal in our patients were the fear of reducing the efficacy of disease modifying drugs (DMDs) upon vaccination as well as distrusting the vaccines and overestimation bias in the power of their innate immunity and potential COVID-19 resistance. Some demographic factors affected vaccination enthusiasm in our study. Our findings did not show significant correlation between the age and comorbidity and vaccine willingness. Only one-third of our patients received their vaccine information from healthcare providers. The majority of them received these data from official broadcasting channels and social media. However, despite several concerns, the willingness of COVD-19 vaccination in the Iranian MS patients is remarkable.

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“…For example, vaccine intentions were considerably higher in the convenience sample at all three time points relative to the web-panel, with 13–18% more participants indicating they would be “extremely likely” to get the vaccine. Such discrepancies are of an important magnitude and are larger than many effects listed as take-away messages from studies using convenience samples (e.g., difference in intentions between subgroups [ 56 , 57 ]). This highlights the importance of taking care not to overgeneralize when using convenience samples and provides valuable information on how researchers can restrain their inferences (e.g., by recognizing that convenience-sample-based estimates of vaccine intentions could be inflated).…”

Section: Discussionmentioning

confidence: 94%

How well do covariates perform when adjusting for sampling bias in online COVID-19 research? Insights from multiverse analyses

et al. 2022

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COVID-19 research has relied heavily on convenience-based samples, which—though often necessary—are susceptible to important sampling biases. We begin with a theoretical overview and introduction to the dynamics that underlie sampling bias. We then empirically examine sampling bias in online COVID-19 surveys and evaluate the degree to which common statistical adjustments for demographic covariates successfully attenuate such bias. This registered study analysed responses to identical questions from three convenience and three largely representative samples (total N = 13,731) collected online in Canada within the International COVID-19 Awareness and Responses Evaluation Study ( www.icarestudy.com ). We compared samples on 11 behavioural and psychological outcomes (e.g., adherence to COVID-19 prevention measures, vaccine intentions) across three time points and employed multiverse-style analyses to examine how 512 combinations of demographic covariates (e.g., sex, age, education, income, ethnicity) impacted sampling discrepancies on these outcomes. Significant discrepancies emerged between samples on 73% of outcomes. Participants in the convenience samples held more positive thoughts towards and engaged in more COVID-19 prevention behaviours. Covariates attenuated sampling differences in only 55% of cases and increased differences in 45%. No covariate performed reliably well. Our results suggest that online convenience samples may display more positive dispositions towards COVID-19 prevention behaviours being studied than would samples drawn using more representative means. Adjusting results for demographic covariates frequently increased rather than decreased bias, suggesting that researchers should be cautious when interpreting adjusted findings. Using multiverse-style analyses as extended sensitivity analyses is recommended. Supplementary Information The online version contains supplementary material available at 10.1007/s10654-022-00932-y.

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Determinants of COVID-19 vaccine acceptance and hesitancy: a cross-sectional study in Saudi Arabia

Cited by 30 publications

References 28 publications

COVID-19 vaccine acceptance: knowledge and beliefs

COVID-19 vaccine acceptance: knowledge and beliefs

COVID-19 Vaccination Willingness and Acceptability in Multiple Sclerosis Patients: A Cross Sectional Study in Iran

How well do covariates perform when adjusting for sampling bias in online COVID-19 research? Insights from multiverse analyses

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