Determinants of long-term outcome in patients after percutaneous stent-assisted intervention on renal artery steno-occlusive atherosclerotic disease

Abstract

guidelines. 1,2 On the one hand, a series of observational studies indicated a significant decrease in blood pressure (BP) and / or creatinine levels. 3-7 Furthermore, a number of studies reported the effect of PTA for RAS on the reduction INTRODUCTION Stent-assisted percutaneous transluminal angioplasty (PTA) of symptomatic atherosclerotic renal artery stenosis (RAS) still remains a controversial issue, which was reflected by a weak level of evidence in the European Society of Cardiology (ESC) and American

Simple clinical scores to predict blood pressure and renal function response to renal artery stenting for atherosclerotic renal artery stenosis

“…The issue is clinically important because improvements in BP and RF translate into cardiovascular events risk reduction [4,6,13,14,15]. We found that eGFR increase by at least 11 ml/min/1.73m 2 , as well as systolic and diastolic BP decrease by 20 and 5mmHg or higher following PTA for ARAS, relate to cardiovascular death (CVD) or stroke risk reduction over 5 years [16].…”

Long-term outcomes and determinants of stenosis recurrence after renal artery angioplasty in hypertensive patients with renovascular disease

“…The immediate result of PTA is characterised by a high success rate and fairly low periprocedural complication rate [5][6][7]. However, the clinical improvement following PTA of RAS is uncertain [5][6][7][8].…”

“…The immediate result of PTA is characterised by a high success rate and fairly low periprocedural complication rate [5][6][7]. However, the clinical improvement following PTA of RAS is uncertain [5][6][7][8]. The effect of PTA is probably a complex issue, as both the effect of PTA on renal function and systolic/diastolic blood pressure (SBP/ DBP), as well as cardiovascular adverse events is at least controversial [6,9,10].…”

“…However, the clinical improvement following PTA of RAS is uncertain [5][6][7][8]. The effect of PTA is probably a complex issue, as both the effect of PTA on renal function and systolic/diastolic blood pressure (SBP/ DBP), as well as cardiovascular adverse events is at least controversial [6,9,10]. Furthermore, the long-term result of PTA is limited by the unwelcome occurrence of recurrent stenosis (RS) that may additionally impact the final effect of PTA.…”

“…Furthermore, the long-term result of PTA is limited by the unwelcome occurrence of recurrent stenosis (RS) that may additionally impact the final effect of PTA. The RS rate following RAS procedures is estimated at 6-40% [5][6][7][8]11]. However, the determinants of RS are poorly established.…”