Determinants of quality of life in Spanish transsexuals attending a gender unit before genital sex reassignment surgery

Gómez‐Gil, Esther; Zubiaurre‐Elorza, Leire; Antonio, Isabel Esteva de; Guillamón, Antonio; Salamero, Manel

doi:10.1007/s11136-013-0497-3

Cited by 56 publications

(77 citation statements)

References 22 publications

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“…Several studies confirm a statistically significant improvement in self-reported quality of life (QoL) in both MTFs and FTMs receiving GAHT [42, 44, 53]. Hormonal intervention is also associated with higher levels of body satisfaction and self-esteem [44, 46•, 47], perhaps with a gender-specific effect.…”

Section: Resultsmentioning

confidence: 99%

Gender-Affirming Hormone Use in Transgender Individuals: Impact on Behavioral Health and Cognition

Nguyen

Chavez

Lipner

et al. 2018

Curr Psychiatry Rep

130

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Purpose of Review With increasing numbers of transgender and gender non-binary individuals presenting for care, knowing how to elucidate the mental health and cognitive outcomes of gender-affirming hormone therapy (GAHT) is necessary. This article reviews the present literature covering GAHT effects on mood, behavioral health, and cognition in these individuals and offers research priorities to address knowledge gaps. Recent Findings Although there are some conflicting data, GAHToverwhelmingly seems to have positive psychological effects in both adolescents and adults. Research tends to support that GAHT reduces symptoms of anxiety and depression, lowers perceived and social distress, and improves quality of life and self-esteem in both male-to-female and female-to-male transgender individuals. Summary Clinically, prescribing GAHT can help with gender dysphoria-related mental distress. Thus, timely hormonal intervention represents a crucial tool for improving behavioral wellness in transgender individuals, though effects on cognitive processes fundamental for daily living are unknown. Future research should prioritize better understanding of how GAHT may affect executive functioning.

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Section: Resultsmentioning

confidence: 99%

Gender-Affirming Hormone Use in Transgender Individuals: Impact on Behavioral Health and Cognition

Nguyen

Chavez

Lipner

et al. 2018

Curr Psychiatry Rep

130

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“…There is little information about the main factors associated to a better sexual QoL. Previous studies on transsexuals analyzing QoL in different domains suggest a positive effect of hormone therapy [35–37]. Hurtado et al.…”

Section: Introductionmentioning

confidence: 99%

Sexual Quality of Life in Gender-Dysphoric Adults Before Genital Sex Reassignment Surgery

Bartolucci

Gómez‐Gil

Salamero

et al. 2015

The Journal of Sexual Medicine

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Introduction Although there is literature on sexuality in gender dysphoria, few studies have been done prior to genital sex reassignment surgery (SRS). Aims To evaluate the perception of sexual QoL in gender-dysphoric patients before genital SRS and the possible factors associated to this perception. Methods The final sample consisted of 67 male-to-female and 36 female-to-male gender-dysphoric adults consecutively attended in a gender unit who had not undergone genital SRS; 39.8% was receiving cross-sex hormonal treatment, and 30.1% had undergone breast augmentation or reduction. Sexual QoL was assessed using the sexual activity facet of the World Health Organization Quality of Life (WHOQOL)-100. Sociodemographic (age, gender, partner relationship) and clinical data (being on hormonal treatment and having undergone any breast surgery) were recorded from the clinical records. Depressive symptoms were assessed using the negative feelings facet of the WHOQOL-100. Personality was assessed using the Revised NEO-Five Factor Inventory. Main Outcome Measures Sexual QoL, negative feelings, hormonal treatment, partner relationship, personality. Results The mean score of the sexual facet was 10.01 (standard deviation = 4.09). More than 50% of patients rated their sexual life as “poor/dissatisfied” or “very poor/very dissatisfied,” around a quarter rated it as “good/satisfied” or “very good/very satisfied,” and the rest had a neutral perception. Three variables were significantly associated with a better sexual QoL: less negative feelings (β = −0.356; P < 0.001), being on hormonal treatment (β = 0.216; P = 0.018), and having a partner (β = 0.206; P = 0.022). Age, sex, having undergone some breast surgery, and personality factors were not associated with their perception. Conclusion This study indicates that before genital SRS, about half of gender-dysphoric subjects perceived their sexual life as “poor/dissatisfied” or “very poor/very dissatisfied.” Moreover, receiving hormonal treatment, low negative feelings, and having a partner are related to a better subjective perception of sexual QoL.

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“…The results of previous cross-sectional studies suggest the positive effects of CSHT in FtM individuals [12–14, 30, 34, 36]. However, a previous study using the MMPI did not show any significant difference [37].…”

Section: Discussionmentioning

confidence: 92%

Efficacy of hormonal and mental treatments with MMPI in FtM individuals: cross-sectional and longitudinal studies

Oda

Kinoshita

2017

BMC Psychiatry

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BackgroundCross-sex hormone treatment (CSHT) is an important option for gender dysphoria (GD) individuals to improve the quality of life. However, in Japan, sex reassignment surgery (SRS) and CSHT for GD had been discontinued until 1998 (over 30 years). After resumption, the number of GD individuals wishing treatment rapidly increased. On the other hand, the number of medical institutions available for evaluation was limited. For this reason, hormonal treatment has been administered to GD individuals requiring the prompt start of CSHT in the absence of mental health assessment by specialists. In this study, we examined the efficacy of CSHT and psychotherapy.MethodsThe participants were 155 female-to-male (FtM) individuals who consulted our gender identity clinic, and were definitively diagnosed. A cross-sectional study was conducted by dividing them into two groups: groups with and without CSHT on the initial consultation (Group CSHT: n = 53, Group no-CSHT: n = 102). In all participants, Minnesota Multiphasic Personality Inventory (MMPI) and blood hormone tests were performed on the initial consultation. In addition, CSHT was combined with psychotherapy for a specific period in Group no-CSHT, and FtM individuals in whom an additional MMPI test could be conducted (Group combined treatment (CT), n = 14) were enrolled in a longitudinal study.ResultsIn the cross-sectional study, there was no significant difference on the MMPI test. In the longitudinal study, there were improvements in the clinical scales other than the Mf scale on the MMPI test. In Group CT, the D, Sc, and Si scale scores on the initial consultation were significantly higher than in Group CSHT. However, there was no clinical scale with a significantly higher value after the start of treatment. The Pd scale score was significantly lower.ConclusionsCSHT improved mental health. Psychotherapy-combined CSHT may further improve it.Trial registrationThe study was reviewed and approved by the Ethics Committee of Kansai Medical University (A comprehensive treatment for gender dysphoria: No. 0314 registered date 10th December 2003), and was approved at UMIN000028102 on 6th July 2017 as retrospectively registered.

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Determinants of quality of life in Spanish transsexuals attending a gender unit before genital sex reassignment surgery

Abstract: Cross-sex hormonal treatment, family support, and working or studying are linked to a better self-reported QoL in transsexuals. Healthcare providers should consider these factors when planning interventions to promote the health-related QoL of transsexuals.

Cited by 56 publications

References 22 publications

Gender-Affirming Hormone Use in Transgender Individuals: Impact on Behavioral Health and Cognition

Gender-Affirming Hormone Use in Transgender Individuals: Impact on Behavioral Health and Cognition

Sexual Quality of Life in Gender-Dysphoric Adults Before Genital Sex Reassignment Surgery

Efficacy of hormonal and mental treatments with MMPI in FtM individuals: cross-sectional and longitudinal studies

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