Determination of [201Tl]Tl(III) in [201Tl]TlCl solutions using HPLC

Production and Clinical Applications of Radiopharmaceuticals and Medical Radioisotopes in Iran

“…Tc-UBI Production. Ubiquicidin (UBI) [29][30][31][32][33][34][35][36][37][38][39][40][41] (TGRAKRRMQYNRR, 1693 Da) is a synthetic cationic chemotactic peptide that preferentially binds to bacterial cell membrane at the site of infection with high sensitivity and specificity. The radioactive peptide was totally synthesized and formulated by the investigators in the country.…”

“…Tc-UBI [29][30][31][32][33][34][35][36][37][38][39][40][41] in differentiation of orthopedic implant infection from sterile inflammation. Nine patients with orthopedic device implants underwent dynamic followed by static whole-body imaging after intravenous (IV) injection of 10 MBq/kg 99m Tc-UBI [29][30][31][32][33][34][35][36][37][38][39][40][41]. Considering bacterial culture from periprosthetic tissue as gold standard, they yielded 100% sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy.…”

“…They stated that these results might be influenced by the fact that all cultures were positive for only Staphylococcus aureus, and diagnostic accuracy would become lower if microorganisms with lower affinity for 99m Tc-UBI (eg, E. coli) were present at cultures. In a study conducted by Doroudi et al, 17 10 diabetic patients with suspected infectious or sterile inflammation in feet, who have not received any antibiotic therapy underwent both three-phase 99m Tc-MDP scan and 99m Tc-UBI [29][30][31][32][33][34][35][36][37][38][39][40][41] scintigraphy. By comparison with culture results, combined techniques lead to a PPV of 100% for detection of infection in diabetic foot.…”

Identification of complexes involving thallium(I) and thallium(III) with EDTA and DTPA ligands by electrospray ionization mass spectrometry

“…High‐performance liquid chromatography (HPLC) with electrochemical detection and inductively coupled plasma mass spectrometry (ICP‐MS) are two techniques which are often used for the determination of speciation forms of Tl. Recently, there has been an interest in the use of electrospray ionization mass spectrometry (ESI‐MS) for detection of metal cations because it has several unique advantages.…”

“…13 Determination of Tl in environmental samples can be challenging due to the very low concentrations often present in surface water (usually below 10-100 ng/L) and non-polluted soil (0.08-1.5 μg/g). 14 High-performance liquid chromatography (HPLC) with electrochemical detection 15 and inductively coupled plasma mass spectrometry (ICP-MS) [16][17][18][19] are two techniques which are often used for the determination of speciation forms of Tl. Recently, there has been an interest in the use of electrospray ionization mass spectrometry (ESI-MS) for detection of metal cations because it has several unique advantages.…”