Determination of aliphatic amines by high-performance liquid chromatography-amperometric detection after derivatization with naphthalene-2,3-dicarboxaldehyde

Study of the naphthalene-2,3-dicarboxaldehyde pre-column derivatization of biogenic mono- and diamines in mixture and fluorescence−HPLC determination

“…Compared with the products formed by derivatization with OPA, the NDA/CN derivatives exhibit improved chemical stability, excitation maxima (420 and 440 nm) in the visible region, efficient chemiluminescence by the peroxyoxalate method and enhanced fluorescence quantum efficiency [41]. NDA has been used for the derivatization of amino acids and peptides [41][42][43][44][45], catecholamines [46][47][48][49], aliphatic amines [50], heterocyclic amines [51,52], aliphatic diamines [53], drugs [54][55][56] and lipids [57]. The main features of these methods are summarized in Electronic supplementary material (ESM) Table S1.…”

Liquid-phase microextraction and fibre-optics-based cuvetteless CCD-array micro-spectrophotometry for trace analysis

“…Derivatization with a maleimide reagent and HPLC with fluorimetric detection [34], or solid-phase microextraction by headspace on-fibre derivation with pentafluorobenzyl bromide and GC-MS [35] have been utilized. Naphthalene-2,3-dicarboxaldehyde in the presence of cyanide has been used for the preparation of thiol derivative and their analysis by capillary electrophoresis with in-column fibreoptics light-emitting diode induced fluorescence detection [36], however, the reaction was too slow, required 4 h for completion, and amino acids and amines also responded to the derivatization reaction [37]. The Ellman reagent, 5,5 -dithio-bis-(2-nitrobenzoate) (DTNB), has frequently been used to determine thiols either via the spectrophotometric detection of intensely yellow thiolate anion formed in the reaction [38,39] or by HPLC of the mixed disulphide [40,41].…”

Determination of aliphatic amines by gas chromatography–mass spectrometry after in-syringe derivatization with pentafluorobenzoyl chloride

“…Several methods have been developed for the analysis of low molecular weight short-chain aliphatic amines (SCAAs) in water and other samples involving derivatization followed by liquid chromatography (LC) coupled with UV [3,4], electrochemical (ECD) [5][6][7] and fluorescence detection [4,[8][9][10][11]. Several reagents for the determination of aliphatic amines by LC with fluorescence detection and post-column online identification by atmospheric pressure chemical ionization mass spectrometry (APCI/MS) [12][13][14][15][16][17][18][19][20] and APCI/MS-MS [21] have been reported.…”