Determination of anabolic steroids in dried blood using microsampling and gas chromatography-tandem mass spectrometry: Application to a testosterone gel administration study

Do dried blood spots have the potential to support result management processes in routine sports drug testing?—Part 2: Proactive sampling for follow‐up investigations concerning atypical or adverse analytical findings

“…Also, if future analytical sensitivity and anti-doping regulations would introduce reporting processes, which increase the prevalence of ATFs in sports drug testing, strategies for efficient follow-up investigations are of essential benefit. One such strategy could exploit the extensive analytical experience with DBS matrix accumulated over more than a decade concerning analytes relevant in doping controls, [39][40][41][42][43][44][45][46][47][48][49] if as above frequently sampled and stored DBS (complementing the monitoring of drug use or drug exposure) are available.…”

Annual banned‐substance review: Analytical approaches in human sports drug testing 2019/2020

“…The relevance and routine applicability of testing serum T in routine doping controls was highlighted by Handelsman and Bermon, who reported on two cases of serial serum T measurements in female athletes, where the pattern of T concentrations was not found to be consistent with any normal physiological profile 80 . The corresponding urinary steroid profile remained unremarkable, a phenomenon also reported by Börjesson, 46 thus underlining the importance of complementing urinary steroidal module of the ABP with serum steroid profile data or, at least, with blood T values determined, for example, from dried blood spots (DBS) 81 …”

Tb3+–atorvastatin doped in poly(ethylene glycol) optical biosensor for selective determination of progesterone and testosterone in serum samples

“…Today, the research eld in which the lanthanide complexes were used as biosensors has a great interest. [20][21][22][23][24][25][26][27][28][29][30] Luminescent optical biosensor Tb (atorvastatin) 3 (Tb-Ator) complex embedded in PEG matrix have many advantages over the mentioned traditional methods. The chemical structure of atorvastatin is presented in Fig.…”

“…Doping of the optical sensors in the polymer matrix increases its stability and durability. [24][25][26][27][28][29][30] The sensor can provide a constant signal response for two years, which makes it 24-fold better balance compared to the lifetime warranted for the chromatographic and electrochemical methods. The source of error of the present work eliminated as it more stables for a long time; it gives a low standard deviation value.…”