Determination of antibiotic residues in the pasteurized milk produced in West Azerbaijan province, North West of Iran

Forouzan, Shirin; Rahimirad, Amir; Seyedkhoei, Roya; Asadzadeh, Jafar; Bahmani, Mahmoud; Ateba, Collins Njie

doi:10.12980/jclm.2.201414j8

Cited by 3 publications

(1 citation statement)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another survey showed that of 251 milk samples analyzed for β-lactam and tetracycline antibiotic residues by the Copan test, 62 (24.8%) were positive ( 39 ). In another study, β-lactam and tetracycline were determined in 848 milk samples collected from West Azerbaijan province by Copan test kit, and 30.14% contained antibiotic residues ( 40 ).…”

Section: Discussionmentioning

confidence: 99%

Simultaneous Screening of Six Families of Antibiotic Residues in Milk Samples by Biochip Multi-array Technology

Yazdanpanah,

Osouli,

Salamzadeh

et al. 2023

Iran J Pharm Res

View full text Add to dashboard Cite

Background: Antimicrobial compounds are used in animal husbandry to prevent and treat bacterial diseases and as illegal growth-promoting agents. Due to the excessive and inappropriate use of antibiotics, the antibiotic residues in milk can cause allergic reactions and antibiotic resistance. A rapid biochip-based method for the multi-analyte screening of 6 families of antibiotic residues (quinolones, ceftiofur, florfenicol, streptomycin, tylosin, and tetracyclines) in milk was validated based on Commission Decision 2002/657 and the European guidance for screening methods for veterinary medicinal products. Methods: This methodology allows the 6 antibiotic families to be detected simultaneously, increasing the screening capacity and reducing costs in test settings. The method's applicability was shown by screening 38 UHT cow milk samples taken from Tehran province, IR Iran. Results: The results showed that the positive threshold T was above Fm, and the CCβ was below the European Commission's Maximum Residue Limit (MRL) (100 ppb for ceftiofur and tetracycline and 50 ppb for tylosin in milk). Norfloxacin was detected in about 8% of the samples and tylosin in 2.63%. The total antibiotic concentration in UHT cow milk samples was lower than the European Commission's MRL. Conclusions: This study showed that the biochip technique is valid for screening tylosin, ceftiofur, streptomycin, tetracycline, norfloxacin, and florfenicol in milk. It was found that the method was easy, quick, and capable of detecting 6 families of antibiotic residues simultaneously from a single milk sample without sample preparation.

show abstract

Section: Discussionmentioning

confidence: 99%

Simultaneous Screening of Six Families of Antibiotic Residues in Milk Samples by Biochip Multi-array Technology

Yazdanpanah,

Osouli,

Salamzadeh

et al. 2023

Iran J Pharm Res

View full text Add to dashboard Cite

show abstract

Dielectrometry of pharmaceutical ingredient solutions at microwaves

Kuznetsova

Eremenko

Shubnyi

et al. 2017

2017 IEEE First Ukraine Conference on Electrical and Computer Engineering (UKRCON)

View full text Add to dashboard Cite

Isolation and Identification of Specific Pathogens, Presence of Antibiotics, Aflatoxins, Pesticide Residues and Industrial Contaminants in Supply Chain of Milk in Selected Coastal Districts of Andhra Pradesh

Kalla¹,

Kutcharlapati²,

Gannavarapu³

et al. 2015

ABB

View full text Add to dashboard Cite

A research study was undertaken to carry out isolation and identification of specific pathogens, presence of antibiotics, aflatoxins, pesticide residues and industrial contaminants in supply chain of milk in selected coastal districts of Andhra Pradesh. The milk is a whole food; it is categorized under perishable foods as it is biologically nutrient liquid that supports the growth of wide variety of microorganisms and is susceptible to spoilage. The quality of milk can be affected by the presence of additional water, detergents, disinfectants, antibiotics, pesticides and pathogens like bacteria, viruses, toxins released by molds such as aflatoxins and heavy metals etc. The raw milk is usually colonized by pathogens like Campylobacter jejuni, enterohemorrhagic Escherichia. coli, Salmonella typhimurium, Listeria monocytogenes, Staphylococcus aureus and Yersinia enterocolitica. The milk samples were collected from vendors of East and West Godavari, Visakhapatnam, Vizianagaram and Srikakulam districts. The milk samples were found to be positive for Tetracycline and Beta lactam antibiotics. The Aspergillus flavus was identified and the colonies producing aflatoxin M1 appeared in yellow color on the Aspergillus agar (M1127). The pesticides and heavy metals in raw and chilled milk samples were detected by atomic absorption spectrophotometer. The pesticide residues were found in raw and chilled milk samples include Lindane, Endosulfan, * Corresponding author. A. Kalla et al. 331Chlorane, Heptachlor and Methoxchlor. The heavy metals like lead, arsenic, zinc and mercury residues were found to occur in raw and chilled milk samples. The hygienic quality of the milk in the current study was found to be poor due to exceeding the standard limits in number of specific pathogens, antibiotic, aflatoxin M1, pesticide and heavy metal residues. Immediate measures are needed to be taken to ensure safety of raw milk in public point of view in Visakhapatnam, East & West Godavari regions.

show abstract

Determination of antibiotic residues in the pasteurized milk produced in West Azerbaijan province, North West of Iran

Cited by 3 publications

References 17 publications

Simultaneous Screening of Six Families of Antibiotic Residues in Milk Samples by Biochip Multi-array Technology

Simultaneous Screening of Six Families of Antibiotic Residues in Milk Samples by Biochip Multi-array Technology

Dielectrometry of pharmaceutical ingredient solutions at microwaves

Isolation and Identification of Specific Pathogens, Presence of Antibiotics, Aflatoxins, Pesticide Residues and Industrial Contaminants in Supply Chain of Milk in Selected Coastal Districts of Andhra Pradesh

Contact Info

Product

Resources

About