Determination of antimicrobial and antiviral properties of IR3535

İyigündoğdu, Zeynep; Kalaycı, Sadık; Asutay, Ayla Burçin; Şahın, Fikrettin

doi:10.1007/s11033-019-04632-x

Cited by 9 publications

(7 citation statements)

References 20 publications

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“…The addition of high amount of NaB (up to 15% by wt.) in sample 6 resulted in marginal effect in tensile strength and elongation at break suggesting NaB most likely acts as a non-reinforcing filler in the composite [ 28 ]. The surface modification of the antimicrobial and antiviral additives or using special coupling agent may improve the interaction with the polymer matrix and the dispersion and mechanical properties.…”

Section: Resultsmentioning

confidence: 99%

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Thermoplastic elastomers containing antimicrobial and antiviral additives for mobility applications

İyigündoğdu¹,

Basar²,

Couvreur³

et al. 2022

Composites Part B: Engineering

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Section: Resultsmentioning

confidence: 99%

“…Adenovirus (AdV), Bovine Coronavirus (BCoV), Poliovirus (PoV), and Murine norovirus (MNV) species specified at Table 2 were used for antiviral studies. Infected cell cultures were prepared as described previously [ 28 ]. The antiviral properties of the TPE samples were investigated according to the ISO 21702:2019 standard.…”

Section: Methodsmentioning

confidence: 99%

Thermoplastic elastomers containing antimicrobial and antiviral additives for mobility applications

İyigündoğdu¹,

Basar²,

Couvreur³

et al. 2022

Composites Part B: Engineering

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“…First, the agar diffusion method was used to determine the antimicrobial activity of ZnB and GnP additives as described previously. [ 27 ] Microbial species used for antimicrobial activity tests (Table 2) were defrosted and cultured onto NA, and PDA for bacteria and fungus, respectively, and incubated at 24 h for bacteria at (35 ± 1) o C, 48 h for yeast at (35 ± 1) o C and 72 h for fungi at (30 ± 1) o C. Colonies were dispersed in sterile PBS to obtain 0.5 McFarland turbidity suspensions. 100 μL bacteria were spread on NA, and 100 μL yeast and fungi were spread on PDA.…”

Section: Methodsmentioning

confidence: 99%

Synergistic effects of zinc borate and graphene on enhanced thermal stability and antimicrobial properties of poly(methyl methacrylate)

İyigündoğdu

2023

Polymer Composites

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The use of graphene nanoplatelets (GnP) as reinforcing material for thermoplastic polymer matrices, polymethyl methacrylate (PMMA) and zinc borate (ZnB), as an antimicrobial and fire‐retardant agent was studied. PMMA‐ZnB and PMMA‐GnP‐ZnB (ZG) composite films were fabricated with different ZnB concentrations (2.5, 5, 10 wt%) by solvent casting method using acetone. The effect of additives on the antimicrobial activity, thermal and mechanical properties, and surface morphologies of the composites were investigated. Antimicrobial surface activity tests were conducted against seven microorganisms, including bacterial and fungal species. An improvement in antimicrobial activity by up to 99.99% with increasing ZnB content was observed. Thermal stability was increased with increasing concentration of ZnB and a combination of ZnB and GnP additions. 10% ZG‐based composites increased the % char residue value of PMMA from 0.5% to 9.3%. The incorporation of the ZnB and GnP into the PMMA matrix resulted in an increase in the calculated limiting oxygen index (LOI). 10% and 50% weight loss temperature increased by 11.7°C and 3.7°C, respectively, for 10% ZG composites. The Young's modulus of the composites increased with increasing ZnB and a combination of ZnB and GnP loading (increasing by 16% to 2033 MPa with the addition of 10 wt% ZG). The commercial application for this study would be in high touch and piano black automotive interior, construction, and medical applications.

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“…The antimicrobial activity of the MEO was carried out using disc diffusion assay as described previously [22]. Microbial strains used for antimicrobial activity tests are given in table 1.…”

Section: Antimicrobial Activity Of Meomentioning

confidence: 99%

Melissa officinalis essential oil loaded polycaprolactone membranes: evaluation of antimicrobial activities and cytocompatibility for tissue engineering applications

Iyigundogdu,

Petek,

Capkin Yurtsever

et al. 2023

Biomed. Mater.

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Antimicrobial biomaterials play important role in tissue engineering applications to protect damaged tissue from infections. The aim of this study is producing antimicrobial polycaprolactone (PCL) membranes by using a plant based antimicrobial agent. Therefore, Melissa officinalis essential oil (MEO) was investigated against 10 types of microorganisms and remarkable antimicrobial activity was demonstrated. PCL:MEO membranes were prepared by solvent casting method by mixing MEO into PCL in various ratios (PCL:0M, PCL:0.25M, PCL:0.5M, and PCL:1M w/w). Water contact angle measurements showed that hydrophilicity of the membranes increased with increasing concentrations of MEO from 103.44o to 83.36o for PCL:0M and PCL:1M, respectively. It was determined that there was an inverse relationship between the MEO concentration and the mechanical properties. Notable antioxidant activity of PCL/MEO membranes was exhibited by the inhibition percent of DPPH which was increased from 24.74% to 44.79% for PCL:0M and PCL:1M, respectively. The antimicrobial activity of MEO was also highly maintained in PCL membranes. For PCL/MEO membranes, at least 99.9% of microorganisms were inhibited. Cytocompatibility of the membranes were investigated by resazurin assay, SEM analysis and DAPI staining. PCL:0.25M and PCL:0.5M membranes supported the viability of L929 cells more than 87% when compared to PCL:0M membranes on day 6. However, the viability of L929 cells on PCL:1M membranes was about 43% indicating significant decrease on cellular activity. In conclusion, PCL:0.25M and PCL:0.5M membranes with their high antimicrobial activity, acceptable mechanical properties and cytocompatible properties, they can be considered as an alternative biomaterial for tissue engineering applications.

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Determination of antimicrobial and antiviral properties of IR3535

Cited by 9 publications

References 20 publications

Thermoplastic elastomers containing antimicrobial and antiviral additives for mobility applications

Thermoplastic elastomers containing antimicrobial and antiviral additives for mobility applications

Synergistic effects of zinc borate and graphene on enhanced thermal stability and antimicrobial properties of poly(methyl methacrylate)

Melissa officinalis essential oil loaded polycaprolactone membranes: evaluation of antimicrobial activities and cytocompatibility for tissue engineering applications

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