Determination of Antimicrobial Resistance of <i>Enterobacteriaceae</i> in Patients with Community Acquired Urinary Tract Infections

Abstract

Abstract:This study was conducted in Port Sudan city, Red Sea state during the period from January to June 2017 to investigate antimicrobial resistance of Enterobacteriaceae isolated from patients suffering from community acquired urinary tract infections. One hundred and fifty urine specimens were collected from patients attended Port Sudan Teaching Hospital. The specimens were cultured on blood agar and Mac Conkey's agar and Cystine Lysine Electrolyte deficient (CLED) agar for primary isolation of pathogens. Identification of the isolates was done by colonial morphology, Gram stain and Routine biochemical tests. Modified Kirby-Bauer disc diffusion method was adopted to determine the resistance rate of Enterobacteriaceae to Imipenem, Ciprofloxacin, Chloramphenicol, Amikacin, Piperacillin, Tetracycline, Ceftazidime and Ticarcillin. Out one hundred and fifty urine specimens examined Enterobacteriaceae was detected in only 49(32.6%) specimens. The results revealed that the antimicrobial resistance of Enterobacteriaceae was as follows: Imipenem (6.1%), Ciprofloxacin (32.6%), Chloramphenicol (48.9%), Amikacin (61.2%), Piperacillin (79.5%), Tetracycline (83.6%), Ceftazidime (89.7%) and Ticarcillin (91.8%). Females were more affected than males (60%) and young adults were more affected than other age groups. Imipenem represented the least sensitive antimicrobial agent (6.1%), while Ticarcillin showed the highest resistance rate.