Intercropping is an excellent system of cropping which achieves a diversified and intensified crop production through better utilization of growth resources and inputs. An experiment was conducted at Teppi Agricultural Research Center from 2011 to 2015 cropping calendar to determine optimum intercropping ratios of coffee and enset that enhances yield productivity and land-use efficiency. The study consisted of six treatments viz., sole cropping of each crop, a staggered planting of both crops, 1:1, 2:1, 3:1 row ratios of coffee to enset, respectively. The experiment was laid out in a randomized complete block design with three replications. A lowland coffee variety (Catimor J-19) and local enset variety were used. The result revealed that the growth parameters of both coffee and enset were not significantly influenced by intercropping, except the internode length of coffee primary branches. However, the yields of the component crops were significantly (p<0.05) affected by different ratios of intercropping. The maximum clean coffee yield was obtained from the sole coffee plot (1127.68 kg ha -1 ) followed by the staggered plot (1082.04 kg ha -1 ). Similarly, the highest kocho (44167 kg ha -1 ) and bulla (1734.70 kg ha -1 ) yields were also found from the sole enset plot. On the other hand, the combined yields of the component crops in all intercropped plots were higher than the sole plots and the LER value was greater than 1. The maximum relative yield advantage of coffee and LER value was recorded from the staggered plot followed by the plot consists of a 3:1 row ratio of coffee to enset. In general, the result was disclosed the agronomic feasibilities of coffee and enset intercropping and the compatibility of the component crops as well. Therefore, it can be concluded that staggered planting of coffee and enset is a suitable cropping arrangement for enhancing the yield productivity of the component crops and ensuring food security for the resource-poor farmers. Thus, the aforementioned planting arrangement can be recommended for farmers and growers in the study area. Nevertheless, additional researches are required in different agro-ecologies of the country with economic feasibility studies to deliver a concrete recommendation.