Determination of bisphenol A: Old problem, recent creative solutions based on novel materials

Abstract

Bisphenol A is a synthetic compound widely used in industry, in the production of polycarbonate, epoxy resins, and thermal paper, among others. Its annual production is estimated at millions of tons per year, demonstrating its importance. Despite its wide application in various everyday products, once in the environment (due to its disposal or leaching), it has high toxicity to humans and animal life, and this problem has been well known for years. Given this problem, many researchers seek alternatives for its monitoring in matrices such as natural water, waste, food, and biological matrices. For this, new advanced materials have been developed, characterized, and applied in creative ways for the preparation of samples for the determination of bisphenol A. This article aims to present some of these important and recent applications, describing the use of molecularly imprinted polymers, metal and covalent organic frameworks, ionic liquids and magnetic ionic liquids, and deep eutectic solvents as creative solutions in sample preparation for the long-standing problem of bisphenol A determination. K E Y W O R D S bisphenol A, carbon nanomaterials, ionic liquids, metal-organic frameworks, molecularly imprinted polymers Article Related Abbreviations: [C 6 (MIM) 2 ]Br 2 , 1-hexyl-di-(3-methylimidazolium) bromide; [C 6 MIM][FeCl 4 ], 1-hexyl-3-methylimidazolium tetrachloroferrate; [C 6 MIM][NTf 2 ], 1-hexyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide; [C 8 C 1 IM][NTf 2 ], 1-octyl-3-methylimidazolium bis((trifluoromethane)sulfonyl)imide; [C 8 MIM][PF

Βisphenol A and its analogs migrated from contact materials into food and beverages: An updated review in sample preparation approaches

“…Adamusova et al in their review published in 2014 focused on selected natural and synthetic estrogens, estrogen conjugates, and chemical additives that can act as estrogen mimics and are used in the plastic industry [5]. Huelsmann et al in their review presented selected applications, describing the use of molecularly imprinted polymers, metal and covalent organic frameworks, ionic liquids and magnetic ionic liquids, and deep eutectic solvents as novel materials in sample preparation [6]. Ouyang and Lu in their review summarized the development of sample pretreatment methods for the analysis of migrating substances from FCMs till 2020 [7].…”

“…Huelsmann et al. in their review presented selected applications, describing the use of molecularly imprinted polymers, metal and covalent organic frameworks, ionic liquids and magnetic ionic liquids, and deep eutectic solvents as novel materials in sample preparation [6]. Ouyang and Lu in their review summarized the development of sample pretreatment methods for the analysis of migrating substances from FCMs till 2020 [7].…”

Synthesis and characterization of pH‐responsive deep eutectic solvent followed by HPLC for trace determination of bisphenol A in water samples

“…Recently, a version of liquid-phase microextraction based on DES has been developed that by changing the pH, the DES enters the sample solution [31][32][33][34][35][36]. In this method, when the hydrophobic DES is added to the sample solution, it does not dissolve in the sample and accumulates on the surface of the test tube due to its lower density [37][38][39]. By adding a strong base and alkalizing the environment, DES is ionized and dissolved in aqueous solution.…”

Environmental contaminants, endocrine disruption, and transgender: Can “born that way” in some cases be toxicologically real?

“…Bisphenol A (BPA) in particular has been among the most heavily synthesized chemicals over the past 3 decades as use of plastics has increased, with annual production reaching millions of tons. 58 Because of growing endocrine disrupting concerns, BPA is more recently being replaced by other bisphenols in plastics production including bisphenol S and bisphenol F, for which there is less available toxicity data.…”