Determination of Cyclobenzaprine in Tablets by High-Performance Liquid Chromatography

Development and validation of dissolution test method for determination of cyclobenzaprine hydrochloride from its formulation using HPLC

“…Cyclobenzaprine Hydrochloride (CBZ) chemically known as 3-(5H-Dibenzo[a,d] 1 annulen-5-ylidene)-N,Ndimethyl-1-propanamine hydrochloride. 2 (Figure 1) The molecular formula & molecular weight of Cyclobenzaprine isC 20 H 21 N and 275.4g/mol.…”

Fabrication of an (α-Mn2O3:Co)-decorated CNT highly sensitive screen printed electrode for the optimization and electrochemical determination of cyclobenzaprine hydrochloride using response surface methodology

“…It is used for muscle spasms from musculoskeletal conditions with sudden onset associated with acute and painful musculoskeletal conditions. 3 Different analytical methods have been prescribed for the quantitative determination of CBZ, including a non-aqueous titration method in U.S.P., 4 spectrophotometric methods, [5][6][7][8][9] HPLC methods, [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] TLC-densitometric method, 18,27,28 GC-MS, [29][30][31][32] and the electrochemical method. 33 Manganese oxide nanoparticles potentially have some remarkably promising applications for sustainable global nanotechnology science.…”