Determination of Eleven Veterinary Drugs in Chicken Meat and Liver

Abstract

Brazil chicken production is around 13 million tons and about a third is exported to over 150 countries, placing Brazil as the world largest chicken meat producer, and therefore it is crucial to follow the legislation of all importer markets. This study conducted a survey by chance in 45 meat industries able to export. Therefore, 2580 chicken meat samples were collected and submitted to 11 analyte extraction and chromatographic verification of compliance in an accredited laboratory. Ten chemical residues (amoxicillin, bacitracin, colistin, dinitolmide + zoalene, spectinomycin, roxarsone, tiamulin, tylosin, trenbolone acetate and virginiamycin) were investigated in chicken meat and one (halofuginone hydrobromide) in chicken liver. The results showed that no compound exceeded the maximum residue limits established by seven legislations. All residue concentrations found were below the method quantification limit, thereby confirming the capability of Brazilian chicken meat industries in complying to foreign markets.

Analysis of Transfer of Tiamulin to Animal Tissue after Oral Administration: An Important Factor for Ensuring Food Safety and Environmental Protection

“…The distribution of tiamulin in animal tissues was studied by gas chromatography with electrochemical detection in pigs and turkeys, by liquid scintillation counting (LSC) in broilers and by gas chromatography (GLC) with an electron capture detector in rabbits. Under the same treatment conditions, similar results were obtained by the LC-MS/MS method described in this study, an equally efficient and accurate method [ 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 ].…”

“…According to Directives 2002/657/EC [ 20 ] and 96/23/EC [ 22 ], tiamulin belongs to group B in Annex I, a minimum of 3 identification points being required for the LC-MS/MS technique to ensure the specificity of the method. In our case, the precursor ion and two transitions were selected, corresponding to two fragmented ions, which means 4 identification points [ 13 ]. The specific ions chosen for tiamulin were the precursor ion 494.5 and two fragment ions 191.9 and 118.6 and, for 8-α-hydroxymutilin, the precursor ion 337.4 and fragment ions 282.8 and 300.8.…”

Agents of Campylobacteriosis in Different Meat Matrices in Brazil

“…The spread of genotypes across different regions of the country was the most identified fact in the strain similarity analysis. This indicates that the perpetuation of similar strains in different regions occurs due to the trade of products and that they can determine the dissemination of these profiles at a global level, considering the importance of the country in the export of animal protein [77].…”