Determination of factors predicting acute appendicitis and perforated appendicitis

Akbulut, Sami; Koç, Cemalettin; Şahin, Tevfik Tolga; Şahin, Emrah; Tunçer, Adem; Demyati, Khaled; Şamdancı, Emine; Çolak, Cemil; Yılmaz, Sezai

doi:10.14744/tjtes.2020.60344

Cited by 30 publications

(46 citation statements)

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“…However, in gender-based evaluation, TBIL levels were signi cantly higher in male patients both in PA and NA groups. In a study by Akbulut et al, a TBIL cut-off ≥ 0.67 is an independent factor predicting acute appendicitis (27). Therefore, our study supports the latest literature in line with our ndings.…”

Section: Discussionsupporting

confidence: 92%

Comparison of Clinical Features Between Patients with Positive and Negative Appendectomy

Çakmak

Mantoğlu

Gönüllü

et al. 2020

Preprint

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Background: The objective of this study was to retrospectively compare clinical features and prognostic values between the patients who were referred to the general surgery clinic of our hospital with the presumed diagnosis of acute appendicitis and underwent positive or negative appendectomy.Methods: Patients were divided into two groups as positive (PA) (n:362) and negative appendectomy (NA) (n:284) and the data obtained were compared between these two groups.Laboratory investigations were performed in all patients, and white blood cell (WBC), mean platelet volume (MPV), neutrophils count (NEU), neutrophils (%) (NEU%), C-reactive protein (CRP) and total bilirubin (TBIL) values were studied.Results: The mean MPV value was found as 7.88 fl in PA groups and 8.09 fl in NA group, and the mean MPV value was not statistically significantly difference in PA group, compared to NA groups (p=0.012). Laboratory parameters were also compared between genders. Accordingly, the mean MPV value was statistically significantly higher in female patients compared to male patients in PA group (p = 0.04). The mean TBIL value was 0.97 mg/dl in PA group and 0.69 mg/dl in NA group, and the mean TBIL value was statistically significantly higher in PA group (p< 0.001). Finally, TBIL value was statistically significantly lower in female patients compared to male patients in NA and PA group (p < 0.05).Conclusions: According to the results of our study, MPV and T. BIL values differ in PA and NA groups depending on gender. Therefore, these values may not be used as specific biomarkers in predicting positive acute appendicitis. We believe that these results will contribute to the literature and will be guiding for future studies.

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Section: Discussionsupporting

confidence: 92%

Comparison of Clinical Features Between Patients with Positive and Negative Appendectomy

Çakmak

Mantoğlu

Gönüllü

et al. 2020

Preprint

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“…However, TBIL levels were within the normal range in both groups. In a study by Akbulut et al, a TBIL cut-off ≥ 0.67 is an independent factor predicting acute appendicitis (27). However, we could not nd any study in the literature investigating the relationship between TBIL and acute appendicitis.…”

Section: Discussionmentioning

confidence: 60%

Comparison of Clinical Features Between Patients with Positive and Negative Appendectomy

Çakmak

Özdemir

2020

Preprint

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Objective: The objective of this study was to retrospectively compare clinical features and prognostic values between the patients who were referred to the general surgery clinic of our hospital with the presumed diagnosis of acute appendicitis and underwent positive or negative appendectomy.Methods: Patients were divided into two groups as positive (PA) (n:425) and negative appendectomy (NA) (n:425) and the data obtained were compared between these two groups. Laboratory investigations were performed in all patients, and white blood cell (WBC), mean platelet volume (MPV), neutrophils count (NEU), neutrophils (%) (NEU%), C-reactive protein (CRP) and total bilirubin (TBIL) values were studied. Results: The mean MPV value was found as 7.66 in PA groups and 7.90 in NA group, and the mean MPV value was statistically significantly lower in PA group, compared to NA groups (p=0.034). The mean TBIL value was 0.75 in PA group and 0.90 in NA group, and the mean TBIL value was statistically significantly lower in PA group (p=0.034).There was no statistically significant difference between the two groups in terms of the other studied laboratory parameters (for all p>0.05).Conclusion: The mean MPV and TBIL values can be used as specific biomarkers in predicting positive acute appendicitis. We believe that these results will contribute to the literature and will be guiding for future studies.

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“…Temple et al, in a prospective study, showed that late admission to hospital was associated with higher perforation rates. Accordingly, the longer the patients wait to go to the hospital, the higher the probability of perforation [ 21 ]. Moreover, following this finding, a higher proportion of patients who underwent an appendectomy at post-COVID-19 period presented complicated appendicitis (8.0% vs. 42.5%, p<0.001) in a study by Cano-Valderrama et al [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

Did the COVID-19 Pandemic Affect the Management of Patients With Acute Appendicitis?

Tazeoğlu¹,

Esmer²,

Arslan³

et al. 2022

Cureus

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Background The coronavirus disease 2019 (COVID-19) pandemic has changed the lives and habits of people all over the world. In this study, it was planned to investigate the effect of the COVID-19 pandemic on the diagnosis and treatment duration of acute appendicitis (AA), morbidity and mortality. Methods The data of patients who were operated on with the diagnosis of AA in our clinic between March 2019 and March 2021, divided into pre-COVID and post-COVID periods, were analyzed. Patients diagnosed with AA, who had the only appendectomy perioperatively, and who had complete preoperative blood analysis and radiological imaging data were included in the study. Results The time from the onset of symptoms to the time of admission to the hospital was statistically significantly longer than in the post-COVID group (p=0.04). During the COVID-19 pandemic period, the use of ultrasonography was statistically significantly reduced (p<0.01); computed tomography use increased (p<0.001). Laparoscopic appendectomy as a surgical technique decreased statistically significantly during the pandemic period (p=0.02). Postoperative complications and the postoperative complication severity degrees were not statistically significant between periods (p=0.24, p=0.68). The risk for the occurrence of postoperative complications in COVID-19 positive patients was statistically higher (p=0.01) (OR: 9.38 95% CI: 1.96 - 44.88). Conclusion The COVID-19 pandemic had caused delays in the admission and diagnosis of patients who might need surgery due to AA. Postoperative complication frequency and complication severity classification were not affected. COVID-19 positivity was a risk factor for complex AA presenting with periappendicular abscess, gangrenous and perforated appendix.

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Determination of factors predicting acute appendicitis and perforated appendicitis

Cited by 30 publications

References 0 publications

Comparison of Clinical Features Between Patients with Positive and Negative Appendectomy

Comparison of Clinical Features Between Patients with Positive and Negative Appendectomy

Comparison of Clinical Features Between Patients with Positive and Negative Appendectomy

Did the COVID-19 Pandemic Affect the Management of Patients With Acute Appendicitis?

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