Determination of fatty acid composition content in the herbal antidiabetic collections

Abstract

It was determined the qualitative composition and the quantitative content of fatty acids in the herbal antidiabetic collection № 3, № 4, № 7, № 13, № 19, which are used in folk medicine for prevention and treatment of diabetes mellitus type 2 in Ukraine by GC/MS method. According to the results it was identified 8 fatty acids in the herbal antidiabetic collection № 3, 13 fatty acids in the herbal antidiabetic collection № 4, 12 fatty acids in the herbal antidiabetic collection № 7, 13 fatty acids in the herbal antidiabetic collection № 13 and 11 fatty acids in the herbal antidiabetic collection № 19. The saturated fatty acids were found to be dominated in the raw plant material. The results of the quantitative research showed that the herbal antidiabetic collection № 3 contains 16.13 mg/g of fatty acids, the herbal antidiabetic collection № 4 – 27.17 mg/g, the herbal antidiabetic collection № 7 – 31.98 mg/g, the herbal antidiabetic collection № 13 – 27.37 mg/g, the herbal antidiabetic collection № 19 – 18.79 mg/g. The GC/MS analysis of the fatty acid composition in the herbal antidiabetic collections has shown that this raw material has a lot of fatty acids, which can have a positive effect for the treatment and prevention of diabetes mellitus type 2.

Analysis of fatty acid composition content in the plant components of antidiabetic herbal mixture by GC-MS

“…In addition, herbal medicines, as a rule, have a wide range of pharmacological properties, which is realized through different groups of phytochemicals (Oh and Jun 2014;Kooti et al 2016;Marchyshyn et al 2020). Combinations of different medicinal plants deserve special attention as such herbal mixtures will have more biologically active substances that will affect all parts of the pathogenetic mechanism of diabetes mellitus and its complications (Savych et al 2020a(Savych et al , b, c, d, e, f, 2021a.…”

“…One of such combinations is an anidiabetic herbal mixture (Urtica dioica L. leaf, Rosa majalis L. fruits, Vaccinium myrtillus L. leaf, Mentha piperita L. herb and Taraxacum officinale L. roots) with established hypoglycemic, hypolipidemic, antioxidant, hepatoprotective, pancreatoprotective activity in pharmacological study in vivo (Savych et al 2020b and the defined phytochemical composition that determines such pharmacodynamics (Savych et al 2020a(Savych et al , 2021a.…”

Analysis of inulin and fructans in Taraxacum officinale L. roots as the main inulin-containing component of antidiabetic herbal mixture

“…One of such combinations is an antidiabetic herbal mixture (Urtica dioica L. leaf, Taraxacum officinale L. roots, Vaccinium myrtillus L. leaf, Rosa majalis L. fruits, Mentha piperita L. herb) with established hypoglycemic, hypolipidemic, antioxidant, hepatoprotective, pancreatoprotective activity in pharmacological study in vivo (Savych et al 2020b, c, d, e, f) and the defined phytochemical composition that determines such pharmacodynamics (Savych et al 2020a;Savych et al 2021a, b, c, d, e, f, g).…”

Determination of carboxylic acids content in the herbal mixtures by HPLC

“…One of these areas is using phytomedicines in the form of monotherapy in the mild stages of the disease and for its prevention, and in combination with traditional therapy for more severe forms of the disease [3,4]. Phytotherapy is a promising and reasonable method, as it has a number of advantagesrelatively low toxicity of herbal medicines, mild pharmacological effect and the ability to use for a long time without significant side effects, the ability to combine well with synthetic drugs [5,6]. The combinations of different medicinal plants deserve particular attention.…”