Determination of Fe(II) and Zn(II) by spectrophotometry, atomic absorption spectrometry and ions chromatography methods in VitrumR

Zareba, S.; Szarwiło, K.; Pomykalski, Arkadiusz

doi:10.1016/j.farmac.2004.03.014

Cited by 13 publications

(9 citation statements)

References 7 publications

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“…Finally Zn 2+ has chemical stability and it undergoes the complexation with selected sensitive chromophoric chelator 19 . Among the many reagents reported so far with heterocyclic rings [20][21][22][23][24] the present heterocyclic pyramidine (Scheme 1) has been shown to serve as an excellent chromophor for the quantification of zinc ions in aqueous solution. The complexation is found to be quantitative in sodium acetate and acetic acid buffer in the presence of pyridinum chloride [pyridine+2 M HCl] as salting out agent.…”

Section: Research Articlementioning

confidence: 99%

Direct and Derivative Spectrophotometric Determination of Zn(II) in Pharmaceuticals

Vani¹,

Subudhi²,

Shivaramaiah³

et al. 2013

Chem Sci Trans

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Heterocyclic compound diamino and dihydroxy-pyramidine was synthesized and proposed as chelating agent for the determination of trace amounts of zinc. Zinc(II) forms the ripen-mangocolour complex with DADHP (Diamino dihydroxypyrimidine) in 1:3 stoichiometric ratio at pH-6 in acetic acid and sodium acetate buffer in the presence of pyrideniumchloride as salting out agent. The maximum absorbance is observed at 480 nm. The Beer's law is obeyed in the range of 1-6 µg. The molar absorptivity (ε) and Sandell's sensitivity of the complex is 0.1484 x 10 4 L mol-1 cm-1 and 0.04545 µg cm-1 respectively. The method was successfully applied for the quantification of Zn(II) in pharmaceutical multi vitamin preparations in the presence of other trace elements. The statistical data evaluated reveals the sensitivity and accuracy of the method than the other methods reported.

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Section: Research Articlementioning

confidence: 99%

Direct and Derivative Spectrophotometric Determination of Zn(II) in Pharmaceuticals

Vani¹,

Subudhi²,

Shivaramaiah³

et al. 2013

Chem Sci Trans

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“…Serum E2, BGP, PTH and CT levels were determined by a radioimmunoassay method [ 33 , 34 ]. Serum, bone and urine Ca, Zn and Cu levels were determined with an atomic absorption spectrophotometric method [ 35 ].…”

Section: Eperimentalmentioning

confidence: 99%

Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats

et al. 2012

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Many commonly consumed foods, herbs and spices contain a complex array of naturally occurring bioactive molecules called phytochemicals, which may confer health benefits. In this study, the impact of LiuWei Zhuanggu Granules (LWZGG) on mineral metabolism in osteopenia development was evaluated. Results showed that serum estrogen, bone gla protein (BGP), and calcitonin (CT) levels, bone Ca, Zn and Cu levels, femur, lumbar vertebrae and trabecular bone density, tibia maximum stress and maximum bending strength were increased, and serum parathyroid hormone (PTH), serum and urine Ca, Zn and Cu levels were decreased in rat bone. It can be concluded that LWZGG is useful to improve bone quality in ovariectomized (OVX) rats.

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“…Several methods, such as atomic absorption spectroscopy (AAS) [1], inductively coupled plasma mass spectrometry (ICP-MS) [2], and inductively coupled plasma atomic emission spectroscopy (ICP-AES) [3] are available to detect metal ions in trace amounts. Although these techniques provide sensitive and accurate results, signi cant drawbacks like non-portability, time-consuming sample processing, high cost, and sophisticated operation [4] have led to researchers' search for alternative methods.…”

Section: Introductionmentioning

confidence: 99%

Bathophenanthroline as Turn-off Fluorescence Sensors for Selective and Sensitive Tetection of Fe(II)

Senanayake

Perera

Costa

et al. 2021

Preprint

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Bathophenanthroline (BPhen) is a versatile bidentate ligand for transition metals, also frequently used as a universal colorimetric probe for Fe(II). The effect of pH on the fluorescence intensity of BPhen and quenching constant of Fe(II) were studied at different pH values using working solutions of 50% ethanol buffered with acetate buffer. Fluorescence intensity of a 3.0 μM Bphen solution in 50% ethanol buffered at pH 6.6 with acetate buffer was selectively quenched by Fe(II) at 25 °C. The LOD of 19 nM at 3.3 σ and the linear range of 63 nM – 224 nM with R2 = 0.9919 revealed that this method is more sensitive than the colorimetric method (detection range =1.8 μM - 18 μM). Quenching of the BPhen-Fe(II) complex is temperature-dependent, which may be due to the increased stability of the formed complex with temperature, supporting a static quenching mechanism. Interference from foreign ions on the fluorescence of the BPhen-iron(II) complex was also studied. A tolerance limit exceeding 5% was observed and recorded. The interference from cations, Ni(II), Co(II), and Cu(II), was relatively higher, while the most common anions showed only a little to no interference. In response time analysis, the fluorescence intensity, which remains constant after 10 minutes, reveals that the system approached equilibrium. This method would be quicker and more accurate than a colorimetric method due to the absence of a solvent extraction step.

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Determination of Fe(II) and Zn(II) by spectrophotometry, atomic absorption spectrometry and ions chromatography methods in VitrumR

Cited by 13 publications

References 7 publications

Direct and Derivative Spectrophotometric Determination of Zn(II) in Pharmaceuticals

Direct and Derivative Spectrophotometric Determination of Zn(II) in Pharmaceuticals

Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats

Bathophenanthroline as Turn-off Fluorescence Sensors for Selective and Sensitive Tetection of Fe(II)

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