Determination of folate in some cereals and commercial cereal-grain products consumed in Poland using trienzyme extraction and high-performance liquid chromatography methods

Gujska, Elżbieta; Kuncewicz, A.

doi:10.1007/s00217-004-1122-z

Cited by 84 publications

(82 citation statements)

References 27 publications

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“…7 The lack of FA gives rise to gigantocytic anemia, leukopenia, mental health issues, psychosis and other diseases. 8 So far, various methods such as high performance liquid chromatography (HPLC), [9][10][11] capillary electrophoresis (CE), 12 surface-enhanced Raman scattering (SERS), 13,14 and enzyme-linked immunosorbent assays (ELISA), 7,15 electrochemiluminescence (ECL) and photoelectrochemical (PEC) methods 16,17 have been applied to FA detection. However, majority of these methods are either of time-consuming, laborious, and requiring expensive facilities.…”

Section: Introductionmentioning

confidence: 99%

11-Mercaptoundecanoic acid capped gold nanoclusters as a fluorescent probe for specific detection of folic acid via a ratiometric fluorescence strategy

et al. 2018

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A novel ratiometric fluorescence strategy is developed for specific detection of folic acid (FA) by using 11-mercaptoundecanoic acid protected gold nanoclusters (AuNCs@MUA). In this design, the fluorescence color of the probe can be switched among red, pink, violet and blue by varying the concentration of FA.AuNCs@MUA possesses strong fluorescence peaking at 612 nm (R-signal) and FA exhibits blue emissive auto-fluorescence at 446 nm (B-signal), showing a large emission shift of $170 nm. When AuNCs@MUA approaches FA through electrostatic binding, the R-signal decreases while the B-signal increases with titration of FA. Based on the above phenomenon, a radiometric analysis platform is constructed for FA target detection, with a wide linear response range from 0 to 20 mM, and an excellent detection limit of 26 nM. This new ratiometric strategy exhibits low background, and wide signal changes in a low concentration range, which presents obvious advantages over most previous FA detections based on single-responsive fluorescence methods. Furthermore, the proposed method is successfully applied to determine FA in human serum samples.

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Section: Introductionmentioning

confidence: 99%

11-Mercaptoundecanoic acid capped gold nanoclusters as a fluorescent probe for specific detection of folic acid via a ratiometric fluorescence strategy

et al. 2018

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“…This is consistent with data from Kariluoto et al [24] which showed that total folate content in different rye varieties ranged from 63 to 78µg/100 g fresh weight. On the other hand, higher folate content in whole rye grain flour were noted by Müller [25] and in a previous study by the authors [23]. This might result from the fact that in an earlier study we purchased rye grains shortly after harvesting and ground them directly prior to extraction.…”

Section: Resultsmentioning

confidence: 76%

“…Mean recoveries of the standards ranged from 81 to 105 %. The lowest value was noted for 5-HCO-H 4 folate and the highest for folic acid [23] Statistical Analysis…”

Section: Recovery Of Folatementioning

confidence: 99%

Folates Stability in Two Types of Rye Breads During Processing and Frozen Storage

Gujska

Michalak

Klepacka

2009

Plant Foods Hum Nutr

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High-performance liquid chromatography was used to study the stability of folate vitamers in two types of rye breads after baking and 16 weeks of frozen storage. Bread made using sourdough seeds contained less total folate (74.6 microg/100 g dry basis, expressed as folic acid) than the whole rye flour (79.8 microg/100 g dry basis) and bread leavened only with baker's yeast (82.8 microg/100 g dry basis). Most importantly, it was generated by a significant decrease in 5-CH3-H4folate form. The baking process caused some changes in folate distribution. Storage of breads at -18 degrees C for 2 weeks did not have a significant effect (p < 0.05) on total folates compared to the content directly after baking. After a 5-weeks storage period, a significant decrease (p < 0.05) in the content of total folates was recorded and it dropped on average by 14% for both type of breads. After a longer period of storage (16 weeks), a 25% loss of folates in the bread made with baker's yeast and a 38% loss in the bread fermented with sourdough seeds was found. Retention of 5-CH3-H4folate and 10-HCO-H2folate forms were much lower in the bread made with a sourdough addition than with baker's yeast only.

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“…Many studies suggest that diminished folate status is associated with enhanced carcinogenesis as folic acid with vitamin B 12 participates in the nucleotide synthesis, cell division and gene expression [27]. Periconceptual supplementation of folic acid has been demonstrated to reduce significantly the incidence and reoccurrence of neural tube defects, such as spina bifida of women [28]. In January 1998, the US Food and Drug Administration introduced mandatory fortification of cereal grain products with folic acid at a concentration of 140 mg/100 g [29].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Studies of Paracetamoland Folic Acid in the Presence of Epinephrineat Poly (Eosin) Modified Electrode: A Voltammetric Study

Cm¹,

Be²,

Jayadevappa³

2017

J Biosens Bioelectron

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Determination of folate in some cereals and commercial cereal-grain products consumed in Poland using trienzyme extraction and high-performance liquid chromatography methods

Cited by 84 publications

References 27 publications

11-Mercaptoundecanoic acid capped gold nanoclusters as a fluorescent probe for specific detection of folic acid via a ratiometric fluorescence strategy

11-Mercaptoundecanoic acid capped gold nanoclusters as a fluorescent probe for specific detection of folic acid via a ratiometric fluorescence strategy

Folates Stability in Two Types of Rye Breads During Processing and Frozen Storage

Electrochemical Studies of Paracetamoland Folic Acid in the Presence of Epinephrineat Poly (Eosin) Modified Electrode: A Voltammetric Study

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