Determination of gardenia yellow colorants in soft drink, pastry, instant noodles with ultrasound-assisted extraction by high performance liquid chromatography-electrospray ionization tandem mass spectrum

Zhou, Wenying; Zhang, Yuan; Yang, Li; Ling, Yun; Li, Hongna; Li, Shaohui; Shou-jun, Jiang; Ren, Zhiyao; Huang, Zhiqiang; Zhang, Feng

doi:10.1016/j.chroma.2016.03.051

Cited by 19 publications

(11 citation statements)

References 21 publications

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“…10−13 Gardenia fruit is a kind of Chinese herb and can also be used as an edible resource, and geniposide is one of the major natural bioactive components in gardenia fruit, which can be used in soft drinks, pastries, and instant noodles. 14 Studies of the beneficial effects of geniposide have been of interest to researchers for decades, and according to our previous study, it is proven that geniposide could attenuate fibrotic progress in injured skeletal muscle. 15 However, the effects of geniposide on muscle fiber- type conversion, glucose metabolism, and the underlying mechanism have not yet been performed.…”

Section: ■ Introductionmentioning

confidence: 99%

Geniposide Improves Glucose Homeostasis via Regulating FoxO1/PDK4 in Skeletal Muscle

Yan

Pan

Zhang

et al. 2019

J. Agric. Food Chem.

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It is well-known that imbalance state of glucose metabolism triggers many metabolic diseases and glucose uptake in skeletal muscle accounts for 90% of body weight. Geniposide is one of the major natural bioactive constituents of gardenia fruit, and the regulation of geniposide on glucose metabolism in skeletal muscle has not yet been investigated. Here, on the basis of microarray analysis, we discovered that geinposide decreased pyruvate dehydrogenase kinase 4 (PDK4) expression in skeletal muscle of mice and subsequently found that geniposide inhibited the expressions of forkhead box O1 (FoxO1), PDK4, and phosphorylated pyruvate dehydrogenase in vitro and in vivo. Moreover, geniposide promoted a switch of slow-to-fast myofiber type and glucose utilization, suggesting that geniposide improved glucose homeostasis. In addition, mechanistic studies revealed that geniposide played above roles by regulating FoxO1/PDK4, which controlled fuel selection via pyruvate dehydrogenase. Meanwhile, effects of geniposide mentioned above could be reversed by FoxO1 overexpression. Together, these results establish that geniposide confers controls on fuel usage and glucose homeostasis through FoxO1/PDK4 in skeletal muscle.

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Section: ■ Introductionmentioning

confidence: 99%

Geniposide Improves Glucose Homeostasis via Regulating FoxO1/PDK4 in Skeletal Muscle

Yan

Pan

Zhang

et al. 2019

J. Agric. Food Chem.

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“…In this research, we investigated the matrix effect first, the matrix effect was examined by calculating the percentage (C%) of signal enhancement or suppression, according to Equation (1): C% = (1 − Ss/Sm) × 100, where Ss is the slope of matrix-matched calibration curve and Sm is the slope of standard solution calibration curve [ 26 ]. In our work, C% <±15% is acceptable.…”

Section: Resultsmentioning

confidence: 99%

A Novel Method for the Determination of Vancomycin in Serum by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Application in Patients with Diabetic Foot Infections

Liu

Zhang

2018

Molecules

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A novel, precise, and accurate high-performance liquid chromatography-tandem mass spectrometry (Q-trap-MS) method was developed, optimized, and validated for determination of vancomycin in human serum using norvancomycin as an internal standard. Effect of different parameters on the analysis was evaluated. ZORBAX SB-C18 column (150 × 4.6 mm, 5 μm) using water (containing 0.1% formic acid, v/v)–acetonitrile (containing 0.1% formic acid, v/v) as a mobile phase was chosen. The calibration curve was linear over the concentration ranges of 1 to 2000 ng/mL for vancomycin. The limit of detection (LOD) and limit of quantification (LOQ) for vancomycin were 0.3 and 1.0 ng/mL. Recoveries were between 87.2 and 102.3%, which gave satisfactory precision. A total of 100 serum samples (from 50 patients with diabetic foot proven Gram-positive infection and 50 nondiabetic patients with pneumonia requiring hospitalization and antibiotic therapy) were analyzed by this method. The trough vancomycin concentrations of diabetic foot infection (DFI) patients and nondiabetic patients were 8.20 ± 2.83 μg/mL (range: 4.80–14.2 μg/mL) and 15.80 ± 5.43 μg/mL (range: 8.60–19.5 μg/mL), respectively. The method is sensitive, precise, and reproducible, it could be applied for routine laboratory analysis of vancomycin in serum samples.

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“…These absorbance values were used for drawing the calibration curve. 30,48 The linear regression equation of the gardenia solution is shown in Figure 5. The abscissa represents the concentration (g/L) and the ordinate represents absorbance.…”

Section: Calibration Curvementioning

confidence: 99%

Dyeing mechanism and photodegradation kinetics of gardenia yellow natural colorant

Jiang

Khan

et al. 2020

Textile Research Journal

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In this study, gardenia yellow solution is used to dye 100% cotton fabric. The dyeing rate curve and adsorption isotherms were recorded to explore the thermodynamic model and to calculate the corresponding parameters. A definite concentration of gardenia yellow solution was placed under the xenon arc lamp for irradiation to test its photodegradability. Absorbance of the solution was measured at different degradation times and the corresponding varying curve of the absorbance was drawn to explore the photodegradation reaction order of the natural colorant and consistent parameters were calculated. The experimental results proved that the dyeing of cotton fabric with gardenia yellow colorant followed the pseudo second order kinetic model whereas adsorption isotherm followed the Langmuir model and the photodegradation process followed the second order kinetic model. Values of different parameters were calculated: reaction rate constant k = 2.26 × 10–3 (mg · L−1)1−m h−1, the correlation coefficient R2 = 0.994, and half decay time t1/2 = 5.82 h.

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Determination of gardenia yellow colorants in soft drink, pastry, instant noodles with ultrasound-assisted extraction by high performance liquid chromatography-electrospray ionization tandem mass spectrum

Cited by 19 publications

References 21 publications

Geniposide Improves Glucose Homeostasis via Regulating FoxO1/PDK4 in Skeletal Muscle

Geniposide Improves Glucose Homeostasis via Regulating FoxO1/PDK4 in Skeletal Muscle

A Novel Method for the Determination of Vancomycin in Serum by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Application in Patients with Diabetic Foot Infections

Dyeing mechanism and photodegradation kinetics of gardenia yellow natural colorant

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