Determination of hydrogen peroxide using a Prussian Blue modified macroporous gold electrode

Abstract

We describe an electrochemical sensor for hydrogen peroxide (H 2 O 2 ) that is making use of Prussian Blue (PB) electrodeposited on a macroporous (mp) gold skeleton electrode. An mp-Cu film was first prepared as a template and the converted into an mp-Au film through a replacement reaction without destructing the structure. Next, a layer of PB was electrochemically deposited on the surface of the mp-Au film. The surface morphology of the electrode was characterized by scanning electron microscopy. Attenuated total reflection infrared spectroscopy and X-ray photoelectron spectroscopy were applied to confirm the structural features. The mp-PB/ Au film electrode displays high electro-catalytic activity for the reduction of H 2 O 2 at a working potential of −50 mV (vs. Ag/AgCl) and is very stable. It has a linear response to H 2 O 2 in the 50 μM to 11.3 mM concentration range and a sensitivity of 767 μA mM −1 cm −2 . The electrode also revealed good selectivity in the presence of electro-active species such as ascorbic acid and uric acid.

Thread‐Based Wristwatch Sensing Device for Noninvasive and Simultaneous Detection of Glucose and Lactate

“…[ 20 ] In addition, water‐based CNT ink provides enables an easier coating process due to its low‐viscosity leading to deeper penetration into the cotton thread‐based working electrode. To further improve the electrocatalytic properties of thread‐based electrode, Prussian blue which is an excellent electrocatalyst of H 2 O 2 [ 21 ] was added into CNT ink. The loading of Prussian blue was investigated in the range between 0 and 7 mg mL −1 as shown in Figure 3c.…”

Validation of in situ diagnostics for the detection of OH and H2O2 in liquids treated by a humid atmospheric pressure plasma jet

“…In the case of the electrochemical H 2 O 2 sensing, high selectivity toward some relevant molecules in biochemistry, like glucose, ascorbic acid, uric acid, and folic acid, was found for other PB-based H 2 O 2 sensors, so electrochemical H 2 O 2 sensing is an option in these scenarios but preliminary experiments should be conducted. [52][53][54] For the case of different plasma sources, it should not be assumed that the high selectivity toward diatomic oxygen is similar for other radical species or allotropes like ozone or for reactive species from nitrogen plasma. Due to their high reactivity, these species have relatively short lifetimes, so their relevance has to be considered from case to case.…”

Visualisation of H2O2 penetration through skin indicates importance to develop pathway-specific epidermal sensing

“…Secondly, it appeared that O 2 , present in air or as a solute, oxidises PW to PB. Though PW/PB-based H 2 O 2 sensing is broadly used, the reactivity of PW with O 2 is rarely reported [40][41][42][43]. and 7 is taken from the permeability experiment performed on splitthickness skin exposed to 0.5 mM H 2 O 2 .…”