Determination of Losartan and Triamterene in Pharmaceutical Compounds and Urine Using Cathodic Adsorptive Stripping Voltammetry

Losartan

“…Ensafi and Hajiarn [24] developed a square-wave voltammetric procedure for the electroanalytical determination of losartan and triamterene in Britton-Robinson buffer (pH 3.0, 0.1 mol/L) as a supporting electrolyte containing 30 ng/mL of copper ions. Opposite to the case of triamterene, losartan cannot be reduced at a mercury electrode alone, but a new peak appears at À0.25 V in the presence of copper due to the formation of a complex between copper(II) and losartan.…”

Curcumin Attenuates Glucose-Induced Monocyte Chemoattractant Protein-1 Synthesis in Aortic Endothelial Cells by Modulating the Nuclear Factor-ĸB Pathway

“…Losartan is a strong nonpeptide antihypertensive agent which exerts its action by specific blockade of angiotensin II receptors [17] . Anti-inflammatory effects of losartan that can be beneficial in abating the risk for atherosclerosis in diabetes are not known.…”

Stability-indicating HPLC-DAD method development, validation, and stress degradation studies for triamterene and xipamide in their combined tablet dosage form

“…Several methods have been reported for the assay of TRI. In pharmaceutical preparations, it has been assayed using micellar electrokinetic chromatography [2], chemometric spectrophotometry [3], micellar liquid chromatography [4], spectrophotometry [5], fluorimetry [6], chemometric fluorimetry [7], potentiometry [8], adsorptive stripping voltammetry [9], thin-layer chromatography (TLC) [10], and capillary electrophoresis [11]. Xipamide (XIP) is a sulfonamide diuretic drug ( Fig.…”