Determination of Normalized Values of the Tricuspid Annular Plane Systolic Excursion (TAPSE) in 405 Spanish Children and Adolescents

Tricuspid Annular Plane Systolic Excursion (TAPSE) and Cardiac Z Score Values in 827 Healthy Turkish Children: Single Center Results

“…Our study revealed very strong correlation Nunez-Gil et al and Koestenberger et al investigated TAPSE values in a large study including both patients and control subjects, including healthy children and children with tetralogy of Fallot and Atrial Septal Defect (ASD), as well as patients with pulmonary hypertension due to congenital heart disease or heart surgery in early childhood. 6,[16][17][18][19] Koestenberger et al studied TAPSE values among 258 premature and mature infants, weighing between 530 g and 4200 g. The mean TAPSE distance was 4.4 mm (z score ±2 SD: 3-5.9) among premature patients, and 10.3 mm (z score ±2 SD: 8.5-12.1) in mature infants. 20 In the present study, the mean TAPSE distance was 9.06 mm (-2 SD: 6.35 mm, + 2 SD: 11.6 mm), and the mean indexed All the patients in the present study were born at a gestational age of 38-40 weeks.…”

“…Rutin ekokardiyografik inceleme yanı sıra sağ ventrikül sistolik fonksiyonları TAPSE ile değerlendirildi. B Bu ul lg gu ul la ar r: : Ortalama TAPSE 17.44 (5,6, ±4,15) mm, ortalama indexlenmiş TAPSE (TAPSE/m 2 ) 25.34 (7,37-76,09, ±11,01) mm/m 2 olarak hesaplandı. Katılımcılar yaş gruplarına göre ele alındıklarında TAPSE ve TAPSE/m 2 z skorları ortalaması sırası ile -0,062 ve 0,229 idi.…”

“…A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Çocuk; triküspid kapak; ventriküler fonksiyon, sağ T Tu ur rk ki iy ye e K Kl li in ni ik kl le er ri i J J C Ca ar rd di io ov va as sc c S Sc ci i 2 20 01 15 5; ;2 27 7( (3 3) ): :9 95 5-- 1 [1][2][3][4][5][6] No comprehensive data on TAPSE percentile and z-scores among healthy Turkish children are currently available. The aim of the present study is to determine the distribution of TAPSE distances and z-scores among a large cohort of healthy Turkish children.…”

Phase 1 study of two inodilators in neonates undergoing cardiovascular surgery

“…A complete anatomical (surgical repair, residual lesions, or pericardial effusions) and functional (shortening/ejection fraction and preload status) evaluation was performed according to a standardized technique (30). Tricuspid annular plane systolic excursion was measured in a subset of patients to assess right-ventricular systolic function (31). Reported normative values in neonates are within 6.6 and 14.5 mm (31).…”

Drs. Mathai and Hassoun reply

“…In general, the existing studies are limited by relatively small sizes. The studies done by Koestenberger and Ravekes and Nunez-Gil and colleagues 5 involve larger populations of children and adolescents and thus provide a useful reference to which values from diseased populations can be compared. In addition, it also remains to be determined whether TAPSE is a sensitive tool for assessing response to therapy in both adults and children; if so, it could be used as an endpoint in clinical trials of therapeutics.…”