Determination of pedigrees and taxa of primates by protein electrophoresis

Lacy, Robert C.; Foster, Melissa L.

doi:10.1111/j.1748-1090.1988.tb03209.x

Cited by 12 publications

References 14 publications

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Captive breeding of squirrel monkeys,Saimiri sciureus andSaimiri boliviensis: The problem of hybrid groups

1998

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The electrophoretic variability of blood proteins coding for up to 32 genetic loci was analyzed in 108 squirrel monkeys (Saimiri sciureus, Saimiri boliviensis, hybrids) from two captive colonies. Twelve polymorphic loci with 31 alleles are reported. The biallelic Ada* locus, G‐statistics and Hardy‐Weinberg genotype equilibria are useful for recognizing hybrids between S. sciureus and S. boliviensis. Backcrosses in hybrid stocks and gene flow in a natural hybrid belt, however, complicate the taxonomic diagnosis of captive specimens: S. sciureus phenotypes imported from Peru possessed the allele Ada*132, which generally characterizes S. boliviensis (or species hybrids). The complex taxonomy of Saimiri spp. Requires careful planning of captive breeding. We suggest a genetic analysis of the founder individuals before their inclusion in the European studbook population and to breed S. sciureus from Guyana separately from Peruvian imports, because the latter bear a greater risk of being taxonomically heterogeneous. Zoo Biol 17:95–109, 1998. © 1998 Wiley‐Liss, Inc.

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Captive breeding of squirrel monkeys,Saimiri sciureus andSaimiri boliviensis: The problem of hybrid groups

1998

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Parallel effects of genetic variation in ACE activity in baboons and humans

Tung

Rudolph

Altmann

et al. 2007

American J Phys Anthropol

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Like humans, savannah baboons (Papio sp.) show heritable interindividual variation in complex physiological phenotypes. One prominent example of such variation involves production of the homeostatic regulator protein angiotensin converting enzyme (ACE), which shows heritable variation in both baboons and humans. In humans, this phenotypic variation is associated with an Alu insertion-deletion polymorphism in the ACE gene, which explains approximately half of the variation in serum ACE activity. We identified a similar Alu insertion-deletion polymorphism in the baboon ACE homologue and measured its frequency in a wild population and a captive population of baboons. We also analyzed the contribution of ACE genotype at this indel to variation in serum ACE activity in the captive population. When conditioned on weight, a known factor affecting ACE activity in humans, age and ACE genotype both accounted for variance in ACE activity; in particular, we identified a significant nonadditive interaction between age and genotype. A model incorporating this interaction effect explained 21.6% of the variation in residual serum ACE activity. Individuals homozygous for the deletion mutation exhibited significantly higher levels of ACE activity than insertion-deletion heterozygotes at younger ages (10-14 years), but showed a trend towards lower levels of ACE activity compared with heterozygotes at older ages (> or =15 years). These results demonstrate an interesting parallel between the genetic architecture underlying ACE variation in humans and baboons, suggesting that further attention should be paid in humans to the relationship between ACE genetic variation and aging.

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Role of cytogenetics for breeding management of squirrel monkey colonies

Fogle

1990

Zoo Biology

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Breeding colonies of squirrel monkeys in zoos are often a mix of Saimiri taxa, which leads to the possibility of hybridization, loss of classification features, and possible reduction of fertility among hybrids. Two zoos, Potawatomi and Brookfield, were used to assess chromosomal composition of colonies. Chromosomes were analyzed from lymphocyte cultures and animals were classified into cytogenetic types. At both zoos there was a predominance of Peruvian types, but hybrids (PeruviadColombian) at Potawatomi and (Peruvian/Colombian and PeruviadGuyanan) at Brookfield were also identified. Analysis of the Brookfield lineage (three generations) revealed karyotypic Peruvians derived from hybrid parents. The Gothic versus Roman arch of periocular white hair shows intermediate or quite variable expression in hybrids and offspring derived from hybrids. Given the relative length of both pericentric inversions and the segments distal to each, a detectable reduction in fertility is predicted when compared with similarsized inversions in humans. Somatic segregation of inversion heterozygotes, which would reconstitute homozygosity and elevate fertility, was not detected.

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Determination of pedigrees and taxa of primates by protein electrophoresis

Cited by 12 publications

References 14 publications

Captive breeding of squirrel monkeys,Saimiri sciureus andSaimiri boliviensis: The problem of hybrid groups

Captive breeding of squirrel monkeys,Saimiri sciureus andSaimiri boliviensis: The problem of hybrid groups

Parallel effects of genetic variation in ACE activity in baboons and humans

Role of cytogenetics for breeding management of squirrel monkey colonies

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