Determination of Solubility and Thermodynamic Properties of Benzophenone in Different Pure Solvents

Abstract

The solubility of benzophenone in various pure solvents, including water, ethanol, 1-propanol, isopropanol, methanol, 1-butanol, isobutanol, 1-octanol, acetonitrile, acetone, ethyl acetate, and methyl acetate, has been measured at temperatures between 278.15 and 318.15 K by a gravimetric method under atmospheric pressure. The solubility obtained in the selected pure solvents increases with the increasing temperature. Several thermodynamic models, including the modified Apelblat model, NRTL model, and Wilson model, were applied to correlate the measured solubility. It was found that the correlated results of the three models were in good agreement with the experimental results. In addition, the dissolution thermodynamic properties of benzophenone in the pure solvents were determined.

Comment on “Measurement and Modeling of Solubility of para-tert-Butylbenzoic Acid in Pure and Mixed Organic Solvents at Different Temperatures” and “Determination of Solubility and Thermodynamic Properties of Benzophenone in Different Pure Solvents”

“…I calculate a value of Δ diss G = −867.0 J mol −1 which differs significantly from the value of Δ diss G = −2825 J mol −1 that Ouyang et al 2 give in Table 4 of their published paper.…”

“…I n recent papers appearing in the Journal of Chemical and Engineering Data Aniya et al 1 and Ouyang et al 2 reported the solubilities of 4-tert-butylbenzoic acid and benzophenone, respectively, in several different organic monosolvents as a function of temperature. As part of each study the authors correlated the variation in the experimental mole fraction solubility with temperature with the modified Apelblat model, the NRTL model, and the Wilson model.…”

“…In the case of the published paper by Ouyang et al 2 the inconsistencies can easily be shown by calculating Δ diss G for benzophenone dissolved in acetone at 318.15 K. I substitute the numerical values of Δ diss H = 15 533 J mol −1 and Δ diss S = 51.548 J mol −1 K −1 from Table 4 of reference 2 into eq 1 above:…”

Solubility Measurement and Thermodynamic Properties of Labetalol Hydrochloride in Different Solvents

“…Δ mix G id , Δ mix H id , and Δ mix S id are the Gibbs energy, the enthalpy, and the entropy of the mixing processes of ideal solutions, and they can be presented as follows 17,19 x exp is the experimental solubility and x cal is the calculated solubility. b Standard uncertainty of T is u(T) = 0.02 K, the relative standard uncertainty of the solubility measurement is u r (x exp ) = 0.14, and the standard uncertainty of pressure is u(P) = 0.3 kPa.…”

“…Δ mix G id , Δ mix H id , and Δ mix S id are the Gibbs energy, the enthalpy, and the entropy of the mixing processes of ideal solutions, and they can be presented as follows , where x i represents the mole fraction of the solute and solvents. For a pure solvent solution, n = 2, and for a binary solvent solution, n = 3.…”