Determination of Some Phenothiazine Drugs Based on Colour Reaction with Potassium Periodate

Spectrophotometric and Stability Indicating High Performance Liquid Chromatographic Determination of Nortriptyline Hydrochloride and Fluphenazine Hydrochloride

“…[1] Various analytical procedures for determination of this drug have been reported. They include spectrophotometry, [20][21][22] spectrofluorimetry, [23,24] titrimetry, [25,26] TLC, [10,27] GC [28] and HPLC. [13,29,30] Electrochemical methods have been recommended.…”

Simultaneous determination of three banned psychiatric drugs in pig feed and tissue using solid‐phase reactor on‐line oxidizing and HPLC‐fluorescence detection

“…Various analytical methods have been reported for the determination of phenothiazines. Available techniques include titrimetry (Issa and Mahrous, ; Walash et al ., ), spectrophotometry (Revanasiddappa and Ramappa, ; Kitamura et al ., ; Basavaiah, ), spectrofluorimetry (White et al ., ; Mohamed et al ., ), chemiluminescence (Kojlo et al ., ; Shi et al ., ), electrochemistry (Razola et al ., ; Daniel and Gutz, ; Huang et al ., ), capillary electrophoresis (Wang et al ., ), flow injection (Daniel and Gutz, ; Zhang et al ., ) and HPLC combined with other techniques (Hayen and Karst, ; Pelander et al ., ; Decaestecker et al ., ).…”

Spectroelectrochemical determination of chlorpromazine hydrochloride by flow-injection analysis

“…The official methods for phenothiazines, listed in the British Pharmacopoeia (BP) and US Pharmacopoeia (USP), consist in the nonaqueous potentiometric titrimetry or spectrophotometry in the ultraviolet region [3,4]. A variety of alternative methods have been reported and the available analytical techniques include: titrimetry with different electrodes or in aqueous phase [5][6][7][8], spectrophotometry in the visible region after oxidation of the phenothiazine [9][10][11][12][13][14][15][16], spectrofluorimetry [17,18], chemiluminescence [19,20], high performance liquid chromatography [21][22][23][24], differential pulse voltammetry [25], differential pulse polarography [26], differential pulse stripping voltammetry [27][28][29][30] and electrophoresis [31][32][33][34]. Chromatographic techniques in combination with electrochemistry and mass spectrometry or fluorescence spectroscopy have also been reported [35], exhibiting excellent selectivity, but requiring expensive instrumentation.…”