Determination of sulfonamides in honey by liquid chromatography–tandem mass spectrometry

A simple hollow fiber renewal liquid membrane extraction method for analysis of sulfonamides in honey samples with determination by liquid chromatography–tandem mass spectrometry

“…However, these techniques are considered expensive and laborious, and frequently result in high blank levels, i.e., high noise signal to blank samples, causing ionic suppres-0021-9673/$ -see front matter © 2010 Elsevier B.V. All rights reserved. doi:10.1016/j.chroma.2010.08.030 sion due to the matrix and reducing the limit of detection obtained by signal-to-noise ratio because of an inefficient sample clean-up [4][5][6][7].…”

Development and validation of a multiclass method for the determination of antibiotic residues in honey using liquid chromatography-tandem mass spectrometry

“…For that reason, it is necessary to include an pretreatment hydrolysis step to break the sugar-sulfonamide bond. Studies have demonstrated that methanol (Bernal, Nozal et al 2009) and hydrochloric acid (Thompson and Noot 2005;Sajid, Na et al 2013;Tölgyesi, Berky et al 2013;Dubreil-Chéneau, Pirotais et al 2014) were the main reagents used to hydrolyze N-glycoside bonds in order to give better recovery.…”

Extraction mechanism of sulfamethoxazole in water samples using aqueous two-phase systems of poly(propylene glycol) and salt

“…The presence of SMX residues in surface water is of concern because they are suspected of being responsible for the appearance of antibioticsresistant bacterial, which may cause potential pollutants to the environment [2]. A variety of methods have been used or proposed to measure sulfonamide residues, such as high performance liquid chromatography [3][4][5][6], enzyme immunoassays [7], gas chromatography [8], and capillary electrophoresis [9]. However, due to a relatively low concentration of SMX in the environment, a relatively simple and effective pre-concentration and clean-up technique is required prior to the analysis of SMX.…”