Determination of ten organic acids by low pressure liquid chromatography

Determination of or-Keto and Hydroxy Acids by High Performance Liquid Chromatography Using Ferric Perchlorate as a Detection Reagent

“…3 Recently, two monitoring systems based on a colorimetric reaction with ferric ion for the determination of organic acids separated on chromatographic columns have been reported by Kasai4,5 and Lunder. 6 The method of Kasai had been used to determine various carboxylic acids which were converted to hydroxamic acids with N,N'-dicyclohexylcarbodiimide and hydroxylamine, but this method was modified to a new colorimetric one which didn't use ferric ion', because the earlier monitoring system was complicated and lacked sensitivity.…”