Determination of the efficacy of using a serine protease gene as a DNA vaccine to protect against Vibrio parahaemolyticus infection in Litopenaeus vannamei

Madsari, Naeem; Maskaew, Siriluk; Obchoei, Sumalee; Kwankaew, Pattamaporn; Senghoi, Wilaiwan; Utarabhand, Prapaporn; Runsaeng, Phanthipha

doi:10.1016/j.dci.2022.104459

Cited by 3 publications

(1 citation statement)

References 45 publications

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“…Humoral immune responses include synthesis and release of certain immune proteins, such as antimicrobial peptides, whereas cellular immune reactions involve phagocytosis, encapsulation and nodulation [3] . These immune responses together generate the defense mechanism against bacterial, fungal, and viral infections in insects, crustaceans and other invertebrates [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Identification and characterization of a Reeler domain containing protein in Procambarus clarkii provides new insights into antibacterial immunity in crustacean

Zhang¹,

Zhou²,

Wang³

2023

Fish and Shellfish Immunology Reports

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Section: Introductionmentioning

confidence: 99%

Identification and characterization of a Reeler domain containing protein in Procambarus clarkii provides new insights into antibacterial immunity in crustacean

Zhang¹,

Zhou²,

Wang³

2023

Fish and Shellfish Immunology Reports

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Advancements in Vibrio vaccines for aquaculture

Zeng,

Sun,

Lai

et al. 2023

Aquacult Int

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Vibrio pathogens and their toxins in aquaculture: A comprehensive review

Vandeputte,

Kashem,

Bossier

et al. 2024

Reviews in Aquaculture

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Aquaculture is an indispensable food source for the growing world population. In the last decades, its intensification has increased the incidence of viral and bacterial infections, emphasizing the need for novel disease management strategies. Vibrionaceae bacteria are widespread in aquatic environments, affecting various host species, including economically important fish, shrimp and bivalves. Also, human consumption of undercooked aquatic food contaminated with Vibrionaceae and/or their toxins poses a threat to human health, leading to conditions such as gastroenteritis, wound infection and sepsis. In addition, small fish and shrimp, in open aquaculture systems, can be eaten by birds that can then carry and spread this pathogen to livestock and humans. Many Vibrionaceae produce toxins, some detrimental or even lethal to the hosts, others affecting surrounding bacteria. This review provides a comprehensive overview of Vibrio toxins affecting aquatic (in)vertebrate, summarizing findings on molecular structures, mechanisms of action and regulation and secretion processes involved. Important toxin classes for microbe–host interactions, such as haemolytic, proteolytic and MARTX toxins, are discussed, along with other toxins like PirAB produced by the AHPND‐causing Vibrio parahaemolyticus. The review also emphasizes the importance of microbe–microbe interactions, particularly the production of bacteriocins by Vibrio species (Vibriocins) and antibacterial effectors produced by the Type 6 Secretion System (T6SS). While whole genome sequencing has identified putative virulence factors that are toxins, many toxins remain partially characterized or uncharacterized. Elucidating their regulation, secretion and molecular characteristics can provide valuable information and lead to novel solutions for managing Vibrio pathogens in aquaculture.

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Determination of the efficacy of using a serine protease gene as a DNA vaccine to protect against Vibrio parahaemolyticus infection in Litopenaeus vannamei

Cited by 3 publications

References 45 publications

Identification and characterization of a Reeler domain containing protein in Procambarus clarkii provides new insights into antibacterial immunity in crustacean

Identification and characterization of a Reeler domain containing protein in Procambarus clarkii provides new insights into antibacterial immunity in crustacean

Advancements in Vibrio vaccines for aquaculture

Vibrio pathogens and their toxins in aquaculture: A comprehensive review

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