Determination of the enantiomer of a cholesterol-lowering drug by cyclodextrin-modified micellar electrokinetic chromatography

Comparison of capillary electrophoresis and liquid chromatography for the enantiomeric separation of ?-phosphonosulfonic acids

“…A limit of 0.5% of the R-enantiomer in a sample concentration of 0.15 mg/ml of the S-enantiomer was determined for both techniques. This equates to a limit of detection of about 0.1%, which is similar to that being reported 22 for similar enantiomeric separations of pharmaceutical compounds.…”

Chiral Resolution ofRR,SS-Hydrobenzoin by Liquid Chromatography Using Borate-Cyclodextrin Complexation

“…The combination of CDs with borate has recently been shown to be a useful tool for the chiral resolution of compounds with vicinal diol structure [2][3][4][5].…”

Enantiomeric purity determination of propranolol by capillary electrophoresis using dual cyclodextrins and a polyacrylamide-coated capillary

“…It is widely used as an antihypertensive [5]. In aqueous solution propranolol decomposes with oxidation of the isopropylamine side chain, accompanied by a reduction in pH and discoloration of the solution.…”