Determination of the ionization constants of weak electrolytes by capillary zone electrophoresis

Cai, Jianyi; Smith, Joel T.; Rassi, Ziad El

doi:10.1002/jhrc.1240150108

Cited by 142 publications

(130 citation statements)

References 3 publications

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“…Intermediate mobility is a function of the dissociation equilibrium of the base [16,34,35]. The electrophoretic mobility of the base is expressed by [36] …”

Section: Theorymentioning

confidence: 99%

“…Most alkaloids of pharmaceutical interest exist in small quantities, and are only sparingly soluble in water, which makes CE a more attractive method for dissociation constant determination than the classical methods [34]. This is the first report on an accurate CE method developed for the determination of dissociation constants of five Strychnos alkaloids from Strychnos nuxvomica L. taking into account the effect of the activity coefficient.…”

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confidence: 99%

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Determination of Dissociation Constants of Strychnos Alkaloids from Strychnos nux-vomica L. by Capillary Electrophoresis

Zhang

et al. 2005

Microchim Acta

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Abstract. An accurate capillary electrophoresis method was developed for the determination of dissociation constants of five Strychnos alkaloids from Strychnos nux-vomica L. The method relies on measuring the effective mobility of the solute as a function of the buffer pH. The mathematical relationship was strictly derived from the fundamental electrophoresis theory and the dissociation equilibrium of a weak base without any simplifications. Careful optimization of the running buffer permitted base-line resolution of the five structurally similar alkaloids.

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“…Intermediate mobility is a function of the dissociation equilibrium of the base [16,34,35]. The electrophoretic mobility of the base is expressed by [36] …”

Section: Theorymentioning

confidence: 99%

mentioning

confidence: 99%

Determination of Dissociation Constants of Strychnos Alkaloids from Strychnos nux-vomica L. by Capillary Electrophoresis

Zhang

et al. 2005

Microchim Acta

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“…Methods for triazine determination in water include separation by HPLC [4][5][6] and GC 7,8 after solid-phase extraction (SPE), [9][10][11] capillary electrophoresis, 12 micellar electrokinetic capillary chromatography, 13 triazine multianalyte immunoassays, 14,15 CL/ ECL immunoassays, 16,17 ELISA, 18,19 ECL, 20 fluorometric methods with dansyl chloride 21 and photochemically-induced fluorometric method with o-phthalaldehyde-2-mercaptoethanol derivitazation. 22 These methods are sensitive and accurate; however, many of these involve expensive methods, and toxic solvents, are slow and require the development of extremely complex gradients for the separation.…”

Section: Introductionmentioning

confidence: 99%

Photodegradation and Flow-Injection Determination of Simetryn Herbicide by Luminol Chemiluminescence Detection

2008

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A novel and simple flow injection chemiluminescence method is reported for the determination of simetryn, a common herbicide. The method is based on the direct oxidation of luminol by the photoproducts of the simetryn in alkaline medium in the absence of catalyst/oxidant. The linear concentration range was 0.01 -2 mg mL -1 simetryn with a correlation coefficient (r 2 ) of 0.9997 and relative standard deviations (RSD; n = 4) in the range of 0.9 -2.3%. The limit of detection (S/N = 3) was 7.5 ng mL -1 with a sample throughput of 100 h -1 . The proposed method has been applied to determine simetryn in natural waters using Sep-Pak C18 cartridges for solid phase extraction (SPE) procedure. The recoveries were in the range of 97 ± 1 to 104 ± 2%. The mechanism of chemiluminescence reaction has also been discussed briefly.

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“…More recently, capillary electrophoresis (CE) has become established as one of the most potentially useful methods of separation [14]. Many typical pollutants including PAH [15,16], pesticides [17,18], and others have been separated and determined by use of the different separation modes of CE. Zemann reported use of coelectroosmotic capillary electrophoresis to separate the priority pollutant phenol [19].…”

Section: Introductionmentioning

confidence: 99%

The determination of chlorophenols in waste water by capillary zone electrophoresis with an organic modifier

Chu

et al. 2002

Chromatographia

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SummaryA capillaryzone electrophoretic method has been optimized to improve seJectivity and resoJution in the analysis of chlorophenols in waste water. Use of a buffer system containing organic solvent dramatically improved the separation of chlorophenols. It was shown that selectivity was strongly affected by electrolyte pH and the presence of organic modifiers. The results show that the determination of all seventeen chlorinated derivatives of phenol in water can be achieved by use of a single organic modifier. For example, with acetone as organic modifier all 17 chlorophenols could be separated and determined within 20 min. The standard deviation of migration times and peak areas of the chlorophenols were in the ranges 0.48 -0.67% and 3.9 -5.1% respectively. Detection linear ranges covered I',,vo orders of magnitude of concentration with correlation coefficients of 0 . 9 9 8 -1.000, except for 4-chlorophenol. Quantitative aspects of capillary zone electrophoresis are also discussed. It was concluded that capillaryzone electrophoresis is a potential method for determination ofchlorophenol pollutants in waste water.

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Determination of the ionization constants of weak electrolytes by capillary zone electrophoresis

Abstract: Summary

Cited by 142 publications

References 3 publications

Determination of Dissociation Constants of Strychnos Alkaloids from Strychnos nux-vomica L. by Capillary Electrophoresis

Determination of Dissociation Constants of Strychnos Alkaloids from Strychnos nux-vomica L. by Capillary Electrophoresis

Photodegradation and Flow-Injection Determination of Simetryn Herbicide by Luminol Chemiluminescence Detection

The determination of chlorophenols in waste water by capillary zone electrophoresis with an organic modifier

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