Determining language laterality by fMRI and dichotic listening

Bethmann, Anja; Tempelmann, Claus; Bleser, Ria De; Scheich, Henning; Brechmann, André

doi:10.1016/j.brainres.2006.11.057

Cited by 103 publications

(74 citation statements)

References 123 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…One participant was left handed, but showed the same lateralization as right handers, as we determined by a standard lateralization test [7]. Participants gave written informed consent to the study, which was approved by the ethics committee of the University of Magdeburg.…”

Section: Participantsmentioning

confidence: 99%

Understanding understanding source code with functional magnetic resonance imaging

Siegmund

Kästner

Apel

et al. 2014

Proceedings of the 36th International Conference on Software Engineering

Self Cite

164

128

View full text Add to dashboard Cite

Program comprehension is an important cognitive process that inherently eludes direct measurement. Thus, researchers are struggling with providing suitable programming languages, tools, or coding conventions to support developers in their everyday work. In this paper, we explore whether functional magnetic resonance imaging (fMRI), which is well established in cognitive neuroscience, is feasible to more directly measure program comprehension. In a controlled experiment, we observed 17 participants inside an fMRI scanner while they were comprehending short source-code snippets, which we contrasted with locating syntax errors. We found a clear, distinct activation pattern of five brain regions, which are related to working memory, attention, and language processing-all processes that fit well to our understanding of program comprehension. Our results encourage us and, hopefully, other researchers to use fMRI in future studies to measure program comprehension and, in the long run, answer questions, such as: Can we predict whether someone will be an excellent programmer? How effective are new languages and tools for program understanding? How should we train developers?

show abstract

Section: Participantsmentioning

confidence: 99%

Understanding understanding source code with functional magnetic resonance imaging

Siegmund

Kästner

Apel

et al. 2014

Proceedings of the 36th International Conference on Software Engineering

Self Cite

164

128

View full text Add to dashboard Cite

show abstract

“…Indeed, when contrasting linguistic tasks to baseline, a bilateral pattern is often observed (Ferstl et al, 2008). Another reason might be that fMRI based lateralization indices are most often derived from a count of activated voxels in each hemisphere (Bethmann et al, 2007;Binder et al, 2000;Cai et al, 2010;Clements et al, 2006;Deppe et al, 2000;Lehéricy et al, 2000;Pujol et al, 1999;Springer et al, 1999;Szaflarski et al, 2002;Szaflarski et al, 2012;Woermann et al, 2003), a method that is very sensitive to the chosen significance threshold (Jones et al, 2011;Seghier, 2008;Suarez et al, 2009). But the divergent findings also point towards the possibility that lateralization may not be uniform across tasks and brain regions.…”

Section: Lateralization Of Broca's and Wernicke's Regions And Vwfamentioning

confidence: 99%

Lateralized task shift effects in Broca's and Wernicke's regions and in visual word form area are selective for conceptual content and reflect trial history

et al. 2014

View full text Add to dashboard Cite

We investigated whether lateralized BOLD-fMRI activations in Broca's region, Wernicke's region and visual word form area (VWFA) reflect task shift costs and to which extent these effects are specific to language related task shifts. We employed a linguistic one-back memory paradigm where participants (n = 58) on each trial responded to whether a given word was the same as the previous word. In concordance with previous findings we found that conceptual shifts (CS), i.e. new words, elicited a strongly left-lateralized response in all three regions compared to repeat words. Words were sometimes presented through the visual modality (read) and sometimes through the auditory modality (spoken). This enabled the study of perceptual modality shifts (PS) relative to trials that stayed in the same modality as the previous trials. Again, we found a strongly left-lateralized effect in all regions. This was independent of whether the word was a CS or not, suggesting that linguistic translation across modalities taxes the same system as CS. Response shifts (RS), on the other hand, when shifting from one response (e.g. reporting a repeat word) to another (e.g. reporting a new word) did not yield an observable left lateralized response in any of the regions, suggesting that the lateralized task shift cost effects in these regions are not shared by all types of task shifts. Lateralization for individual tasks was found to be correlated across brain regions, but not across tasks, suggesting that lateralization may not be a unitary phenomenon, but vary across participants according to task demands. Both response time and lateralization were found to reflect the demands not only of the current trial but also of the previous trial, illustrating the context dependency of even simple cognitive tasks.

show abstract

“…Bethmann et al 24 made a comparison between these 2 tests in 30 healthy people. The authors went to a conclusion that there was short difference between the ears, suggesting that the DLT can not be used with the aim of determine a laterality of the language, on the opposite of the fMRI, that efficiently identified the dominant hemisphere of the participants.…”

Section: Language Hemisphere Dominance: Dlt and Fmrimentioning

confidence: 99%

Language brain dominance in patients with refractory temporal lobe epilepsy: a comparative study between functional magnetic resonance imaging and dichotic listening test

Fontoura

Branco

Anés

et al. 2008

Arq. Neuro-Psiquiatr.

View full text Add to dashboard Cite

-Purpose: To identify brain dominance for language functions with DLT and correlate these results with those obtained from fMRI in patients suffering from intractable temporal lobe epilepsy. Method: This study reports on 13 patients who underwent pre-surgical epileptic evaluation between April and October 2004 at the Epilepsy Surgery Program, Hospital Sao Lucas, PUCRS. In DLT, dominance was assessed through a consonant-vowel task, whereas in fMRI patients performed a verb generation task. Results: Our results identified a correlation between the fMRI lateralization index and the DLT ear predominance index and reply difference index (r=0.6, p=0.02; Pearson Correlation Coefficient), showing positive correlation between results obtained from fMRI and DLT. Conclusion: DLT was found to significantly correlate with fMRI. These findings indicate that DLT (a non-invasive procedure) could be a useful tool to evaluate language brain dominance in pre-surgical epileptic patients as it is cheaper to perform than fMRI.KEy wORDS: dichotic listening test, functional magnetic resonance imaging, refractory temporal lobe epilepsy, brain dominance, language.Determinação de dominância cerebral para linguagem em pacientes com epilepsia refratária de lobo temporal: estudo comparativo entre ressonância magnética funcional e teste de escuta dic�tica teste de escuta dic�tica Resumo -Objetivo: Identificar a dominância cerebral para funções de linguagem através do teste de escuta dicótica (TED) e correlacionar com os resultados de ressonância magnética funcional (RMf) em pacientes com epilepsia refratária de lobo temporal. Método: Foram estudados 13 pacientes com epilepsia refratária de lobo temporal, que realizaram avaliações pré-cirúrgicas no período de abril a outubro de 2004 no Programa de Cirurgia de Epilepsia do Hospital São Lucas da PUCRS. Realizada investigação da dominância hemisférica para linguagem através do TED Consoante-Vogal e da RMf pela geração de verbos. Resultados: Verificou-se a existência de correlação entre os índices de lateralidade (RMf) e os índices de predomínio de orelha e de diferença de resposta (TED) (r=0,6, p=0,02). Conclusão: Existe correlação entre os resultados obtidos através da RMf (índice de lateralidade) e do TED (índice de predomínio de orelha e índice de diferença de resposta) em pacientes com epilepsia refratária de lobo temporal.PALAVRAS-CHAVE: teste de escuta dicótica, ressonância magnética funcional, epilepsia temporal refratária, dominância cerebral, linguagem.

show abstract

Determining language laterality by fMRI and dichotic listening

Cited by 103 publications

References 123 publications

Understanding understanding source code with functional magnetic resonance imaging

Understanding understanding source code with functional magnetic resonance imaging

Lateralized task shift effects in Broca's and Wernicke's regions and in visual word form area are selective for conceptual content and reflect trial history

Language brain dominance in patients with refractory temporal lobe epilepsy: a comparative study between functional magnetic resonance imaging and dichotic listening test

Contact Info

Product

Resources

About