Determining the lowest trypan blue concentration that satisfactorily stains the anterior capsule

Yetik, Hüseyin; Devranoğlu, Kazım; Özkan, Şehirbay

doi:10.1016/s0886-3350(02)01217-8

Cited by 47 publications

(36 citation statements)

References 7 publications

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“…Unfortunately, the study did not have a control group for comparison. 11 This technique of staining under viscoelastic was also assessed by Ernus et al 12 and the postoperative outcomes were similar to the fellow eye with senile cataract undergoing phacoemulsification without staining.…”

Section: Introductionmentioning

confidence: 82%

“…Capsular staining under air, however, was criticized as time-consuming and it may be difficult to reform the anterior chamber with a single air bubble. 11 An alternative staining technique without the use of an air bubble was suggested by Yetik et al 11 and involves injection of dispersive viscoelastic. The underside of the injection cannula was used to spread the dye mechanically to obtain homogenous stain.…”

Section: Introductionmentioning

confidence: 99%

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A prospective study on trypan blue capsule staining under air vs under viscoelastic

Wong

Lai

Lee

et al. 2005

Eye

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Aim To compare the safety and effectiveness of trypan blue capsule staining under air vs under viscoelastic. Methods A total of 52 consecutive patients planned for phacoemulsification of white mature cataract were randomly assigned to trypan blue staining under air or under viscoelastic. Perioperative changes in bestcorrected visual acuity (BCVA), central corneal thickness (CCT), and endothelial cell density (ECD) were compared between the two groups. The differences in operating and phacoemulsification times, staining pattern, and complications between the two groups were also recorded. Results Phacoemulsification of white mature cataract was performed in 50 (96%) eyes. The median preoperative BCVA was hand movement. No significant differences in the baseline characteristics were found between the two groups. At 3 months after phacoemulsification, the median BCVA improved to 0.8. The mean CCT returned to preoperative level by 1 month postoperatively and the mean ECD loss was 11.9% 3 months postoperatively. No significant differences in median BCVA, mean phacoemulsification and operation times, mean CCT, and mean ECD were found between the two groups. Conclusions Trypan blue staining of the anterior lens capsule under air or under viscoelastic were similarly effective and safe methods for the phacoemulsification of white mature cataract.

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Section: Introductionmentioning

confidence: 82%

Section: Introductionmentioning

confidence: 99%

A prospective study on trypan blue capsule staining under air vs under viscoelastic

Wong

Lai

Lee

et al. 2005

Eye

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“…Several techniques for staining the anterior lens capsules have been used, such as direct vital dye application in the anterior chamber under an air bubble or not, dye application under a viscoelastic substance in the anterior chamber, and subcapsular application (Pandey et al 2000, Yetik et al 2002, Xiao et al 2004, Allen et al 2006. The last three techniques are indicated for reducing the possible toxic effects of the dye to the corneal endothelium (Yetik et al 2002, Allen et al 2006.…”

Section: Discussionmentioning

confidence: 99%

“…The last three techniques are indicated for reducing the possible toxic effects of the dye to the corneal endothelium (Yetik et al 2002, Allen et al 2006. In this research, the use of the brilliant blue intracameral dye without another substance or air bubble was done to produce direct contacts between the vital dye and the corneal endothelium.…”

Section: Discussionmentioning

confidence: 99%

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Effects of intracameral brilliant blue on the corneal endothelium of swine: in vitro study

et al. 2016

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ABSTRACT.-Terzariol M., Hünning P.S., Brambatti G., Albuquerque L., Neumann C. & Pigatto J.A. T. 2016 The aim was to investigate the ultrastructural changes in the corneal endothelium of pigs induced by intracameral 0.05% brilliant blue. Twenty swine corneas were separated into two groups, the right eye bulbs (control group) and the left eye bulbs (experimental group) of the same animal. All the eye bulbs were evaluated with specular microscopy. The cornea of the right eye bulbs was excised and in the left eye bulbs 0.2ml of 0.05% brilliant blue vital dye (OPTH-blue ® ) was injected into the anterior chamber, where it remained for one minute. Then the anterior chamber was cleaned with a balanced salt solution injection and the cornea was excised too. All the corneas were evaluated by scanning electron microscopy to evaluate the changes on the endothelium caused by the brilliant blue dye. There were no significant differences between the right corneal endothelium cells and the left corneal endothelium cells with scanning electron microscopy after intracameral use of 0.05% brilliant blue dye. The 0.05% brilliant blue dye concentration did not cause deleterious effects for the swine corneal endothelium after intracameral use and can be a choice for safe staining of the anterior capsule of the lens in cataract surgery.INDEX TERMS: Eye, brilliant blue 0.05%, toxicity, corneal endothelium, swine.

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V.A.3. Chromodissection in Vitreoretinal Surgery

Haritoglou

Gandorfer

2014

Vitreous

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Determining the lowest trypan blue concentration that satisfactorily stains the anterior capsule

Abstract: As trypan blue is a potentially carcinogenic vital dye and its possible long-term side effects are unknown, the lowest effective concentration should be used. A concentration lower than 0.1% was effective in staining the anterior capsule even under dispersive viscoelastic material.

Cited by 47 publications

References 7 publications

A prospective study on trypan blue capsule staining under air vs under viscoelastic

A prospective study on trypan blue capsule staining under air vs under viscoelastic

Effects of intracameral brilliant blue on the corneal endothelium of swine: in vitro study

V.A.3. Chromodissection in Vitreoretinal Surgery

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