Determining the number of intraparotid lymph nodes: Postmortem examination

Ergün, Selma Sönmez; Gayretli, Özcan; Büyükpınarbaşılı, Nur; Yıldız, Kemalettin; Gürses, İlke Ali; Avşar, Abdullah; Cavlak, Mehmet

doi:10.1016/j.jcms.2013.09.011

Cited by 35 publications

(26 citation statements)

References 23 publications

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“…Although Klussmann et al [8] described pathologic neck metastasis was detected in only 33.3% of the patients with positive IPNs, both Lim et al [12] and Nisa et al [13] reported there was relatively high reliability of IPN metastasis in predicting neck metastasis. The viewpoint was also supported by our finding.…”

Section: Discussionmentioning

confidence: 99%

“…The IPNs are classified into superficial and deep lobe nodes [12], therefore the IPNs are significantly affected by different surgical procedures, compared to total parotidectomy, lateral or superficial parotidectomy has a lower probability to find all relevant IPNs, but in the above-mentioned researches [8–11], a certain number of procedures of lateral or superficial parotidectomy are included, therefore the exact IPN metastasis rate as well as its survival impact in patients with MEC remains unclear.…”

Section: Introductionmentioning

confidence: 99%

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Role of intraparotid node metastasis in mucoepidermoid carcinoma of the parotid gland

2019

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s Background Prognostic factors for parotid mucoepidermoid carcinoma (MEC) usually include disease grade, tumor stage, node stage, perineural invasion, and lymphovascular invasion. But the role of intraparotid nodes (IPNs) remains unclear, therefore, the study aimed to analyze the significance of IPNs in predicting recurrence in parotid MEC. Methods One hundred and ninety patients were included for analysis finally. Data regarding demography, pathological characteristics, IPN metastasis, TNM stage, follow up was collected and evaluated. The recurrence-free survival (RFS) was the main study endpoint. Results A total of 47 (24.7%) patients had IPN metastasis, and the IPN metastasis was significantly related to tumor stage, pathologic N stage, lymph-vascular invasion, perineural invasion, and disease grade. Recurrence occurred in 34 (17.9%) patients. For patients without IPN metastasis, the 10-year RFS rate was 88%, for patients with IPN metastasis, the 10-year RFS rate was 54%, the difference was significant ( p < 0.001). Further Cox model analysis confirmed the independence of IPN metastasis in predicting the prognosis. Conclusion The IPN metastasis is relatively common in parotid MEC, it is significantly related to tumor stage and disease grade, IPN metastasis means worse recurrence-free survival.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Role of intraparotid node metastasis in mucoepidermoid carcinoma of the parotid gland

2019

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“…According to anatomic studies, the intraparenchymal lymphatic network of the parotid gland is not developed to any great extent, containing approximately only three to four lymph nodes in total . Sönmez Ergün et al, in an anatomic research of 84 glands (42 fresh cadavers), could find no lymph nodes in four of 84 superficial lobes and in 58 of 84 deep lobes . How often is the locoregional lymphatic network attacked by a small (T1–T2) nonaggressive (low‐grade) parotid tumor?…”

Section: Discussionmentioning

confidence: 99%

“…12 S€ onmez Erg€ un et al, in an anatomic research of 84 glands (42 fresh cadavers), could find no lymph nodes in four of 84 superficial lobes and in 58 of 84 deep lobes. 12 How often is the locoregional lymphatic network attacked by a small (T1-T2) nonaggressive (low-grade) parotid tumor? According to the literature, for T1 to T2 tumors of the parotid gland, irrespective of the histologic type, the reported rates of lymph node metastasis range from 7% 13 to 16%.…”

Section: Discussionmentioning

confidence: 99%

Extracapsular dissection as sole therapy for small low‐grade malignant tumors of the parotid gland

2017

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“…3,4 Cadaveric studies have demonstrated that lymph nodes are consistently present both superficial and deep to the facial nerve within the parotid gland. [5][6][7] When a total parotidectomy has been performed for metastatic melanoma and other parotid malignancy, metastatic disease has been found in lymph nodes deep to the facial nerve. 4,8,9 For metastatic melanoma, a 7% parotid bed recurrence rate after superficial parotidectomy is quoted in the literature, 10 compared with a 0% parotid bed recurrence rate after total parotidectomy.…”

Section: Introductionmentioning

confidence: 99%