Déterminisme neuro humoral de l'adaptation de l'intestin résiduel après entérectomie

Laplace, J.P.

doi:10.1051/rnd:19830501

Cited by 4 publications

(1 citation statement)

References 134 publications

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“…This was confirmed as it was shown that compensatory mucosal hypertrophy after small bowel resection was severely impaired by vagal deafferentation [101,102]. This suggested that, besides intrinsic control factors of epithelial renewal, the visceral sensitivity supported by vagal afferences might be a determinant of true adaptation as a result of the homeostatic control of functional digestive ability.…”

Section: Central and Peripheral Control Of Food Intake And Digestive supporting

confidence: 60%

Forty years of achievement in french research on digestive physiology in the pig

Laplace¹,

Aumaı̂tre²,

Rérat³

2001

Reprod. Nutr. Dev.

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-The contribution of the research group set up by Rérat in the early 1960s in Jouy-en-Josas, and then expanded to Rennes, is summarised. As digestive processes are a major key to the nutritional status of monogastric animals, original methodologies based on advanced experimental surgery were developed in the pig to quantify the digestion and absorption yield, to know their factors of variation, and to understand their physiological and nutritional consequences. The group also extended its expertise to the control of food intake, the role of the nervous system and regulatory peptides, and several biomedical gut-related topics. pig / digestion / absorption / neurohumoral regulation / adaptationRésumé -Réalisations et succès de la recherche française : quarante ans de physiologie digestive chez le porc. Dès le début des années 60, un groupe de recherches a été constitué à l'initiative de A. Rérat à Jouy-en-Josas pour étudier divers aspects de la physiologie digestive chez le porc. Leur exploration a fourni des clés essentielles pour la maîtrise du statut nutritionnel chez cette espèce monogastrique, et un instrument d'amélioration de la production porcine. Ce groupe s'est élargi au fil des années et a même essaimé dans les années 80, notamment à Rennes. Il a apporté une contribution essentielle par le développement de méthodologies nouvelles généralement basées sur une chirurgie expérimentale très élaborée. Ces approches ont fourni de nombreux travaux originaux qui ont permis de décrire les processus de digestion (motricité, transit, sécrétions, hydrolyses enzymatiques

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Section: Central and Peripheral Control Of Food Intake And Digestive supporting

confidence: 60%

Forty years of achievement in french research on digestive physiology in the pig

Laplace¹,

Aumaı̂tre²,

Rérat³

2001

Reprod. Nutr. Dev.

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show abstract

Interaction of vasoactive intestinal peptide with rat small intestinal epithelial cells after intestinal resection

et al. 1985

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Specific binding of vasoactive intestinal peptide (VIP) and VIP-stimulated cyclic AMP accumulation were studied in small intestinal epithelial cells (both of crypt and villous levels) 3, 7 and 14 d after a 60% resection of the small intestine. The affinity, but not the binding capacity, of VIP receptors decreased during the adaptive hyperplastic response. Basal cyclic AMP levels were similar in cells of both control and resected rats. Resection induced a decrease of potency, but not of efficiency, of VIP on the stimulation of cyclic AMP accumulation.

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L’Homme, victime de son cerveau ?

Laplace¹

2008

Cahiers de Nutrition et de Diététique

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Déterminisme neuro humoral de l'adaptation de l'intestin résiduel après entérectomie

Abstract: Summary. Neurohumoral

Cited by 4 publications

References 134 publications

Forty years of achievement in french research on digestive physiology in the pig

Forty years of achievement in french research on digestive physiology in the pig

Interaction of vasoactive intestinal peptide with rat small intestinal epithelial cells after intestinal resection

L’Homme, victime de son cerveau ?

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