Deterministic Design of Thin-Film Heaters for Precise Spatial Temperature Control in Lab-on-Chip Systems

Martinez-Quijada, Jose; Caverhill-Godkewitsch, Saul; Reynolds, Matthew; Sloan, David; Backhouse, C.; Elliott, D.G.; Sameoto, Dan

doi:10.1109/jmems.2016.2536561

Cited by 5 publications

(2 citation statements)

References 36 publications

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“…In this case, our insulated design shows a greater efficiency improvement, and we see the power required to maintain 35 °C, 45 °C, and 55 °C drops from 727 mW, 965 mW, and 1200 mW (non-insulated) to 255 mW, 340 mW, and 428 mW (insulated), or 65.0, 64.8, and 64.5% saving. The above power values required for our heater design are in line with Martinez-Quijada et al, who showed clean-room fabricated thin-film heaters that consumed 1130 mW to elevate a 1 cm chip to 95 °C in 22 °C ambient air [ 39 ]. When we drive our insulated heater design to 95 °C, the simulated power consumption is comparable at 900 mW.…”

Section: Resultssupporting

confidence: 75%

An Energy Efficient Thermally Regulated Optical Spectroscopy Cell for Lab-on-Chip Devices: Applied to Nitrate Detection

et al. 2021

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Reagent-based colorimetric analyzers often heat the fluid under analysis for improved reaction kinetics, whilst also aiming to minimize energy use per measurement. Here, a novel method of conserving heat energy on such microfluidic systems is presented. Our design reduces heat transfer to the environment by surrounding the heated optical cell on four sides with integral air pockets, thereby realizing an insulated and suspended bridge structure. Our design was simulated in COMSOL Multiphysics and verified in a polymethyl methacrylate (PMMA) device. We evaluate the effectiveness of the insulated design by comparing it to a non-insulated cell. For temperatures up to 55 °C, the average power consumption was reduced by 49.3% in the simulation and 40.2% in the experiment. The designs were then characterized with the vanadium and Griess reagent assay for nitrate at 35 °C. Nitrate concentrations from 0.25 µM to 50 µM were tested and yielded the expected linear relationship with a limit of detection of 20 nM. We show a reduction in energy consumption from 195 J to 119 J per 10 min measurement using only 4 µL of fluid. Efficient heating on-chip will have broad applicability to numerous colorimetric assays.

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Section: Resultssupporting

confidence: 75%

An Energy Efficient Thermally Regulated Optical Spectroscopy Cell for Lab-on-Chip Devices: Applied to Nitrate Detection

et al. 2021

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“…One of the important components in functional windows is transparent and flexible thin film heaters (TFHs) that effectively removed the frost on curved windows. To fabricate high performance transparent and flexible TFHs, high quality transparent electrodes with low sheet resistance, high transparency, and outstanding flexibility are required because the heating temperature, thermal response time, and transparency of the windows are affected by electrical and optical properties of the electrodes . Sn‐doped In 2 O 3 (ITO) film coated on glass substrates has been mainly used as a transparent electrode for rigid‐type TFHs due to its low sheet resistance and high transparency.…”

Section: Introductionmentioning

confidence: 99%

Flexible Metal/Oxide/Metal Transparent Electrodes Made of Thermally Evaporated MoO₃/Ag/MoO₃ for Thin Film Heaters

Park

Kim

2018

Physica Status Solidi (a)

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The authors report on thermally-evaporated MoO 3 /Ag/MoO 3 multilayer films as a flexible and transparent electrode for high performance flexible thin film heaters (TFHs). Using thermal evaporation, the authors obtain highly flexible MoO 3 /Ag/MoO 3 multilayer films on colorless polyimide substrate without plasma damage. To optimize the thickness of the Ag interlayer, the authors investigate the electrical, optical, morphological, and mechanical properties of MoO 3 /Ag/MoO 3 multilayers as a function of Ag interlayer thickness. Based on a figure of merit value, the authors obtain an optimal MoO 3 /Ag/MoO 3 electrode with a low sheet resistance of 3.17 Ohm/square, a high optical transmittance of 77.85%, and critical bending radius of 1 mm, which are acceptable for fabrication of TFHs. The flexible TFHs (25 Â 25 mm 2 ) fabricated on a thermally evaporated MoO 3 /Ag/MoO 3 electrode shows a high saturation temperature of 118 C even at a low input power of 2.5 W (input voltage 2.5 V) due to very low sheet resistance. Successful operation of the flexible TFHs indicate that the thermally-evaporated MoO 3 /Ag/MoO 3 film is a promising alternative transparent electrode to substitute sputtered Sn-doped In 2 O 3 (ITO) films for highly transparent and flexible TFHs.

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Development of a disposable and easy-to-fabricate microfluidic PCR device for DNA amplification

Mashouf

Talebjedi

Tasnim

et al. 2023

Chemical Engineering and Processing - Process Intensification

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Deterministic Design of Thin-Film Heaters for Precise Spatial Temperature Control in Lab-on-Chip Systems

Cited by 5 publications

References 36 publications

An Energy Efficient Thermally Regulated Optical Spectroscopy Cell for Lab-on-Chip Devices: Applied to Nitrate Detection

An Energy Efficient Thermally Regulated Optical Spectroscopy Cell for Lab-on-Chip Devices: Applied to Nitrate Detection

Flexible Metal/Oxide/Metal Transparent Electrodes Made of Thermally Evaporated MoO₃/Ag/MoO₃ for Thin Film Heaters

Development of a disposable and easy-to-fabricate microfluidic PCR device for DNA amplification

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Deterministic Design of Thin-Film Heaters for Precise Spatial Temperature Control in Lab-on-Chip Systems

Cited by 5 publications

References 36 publications

An Energy Efficient Thermally Regulated Optical Spectroscopy Cell for Lab-on-Chip Devices: Applied to Nitrate Detection

An Energy Efficient Thermally Regulated Optical Spectroscopy Cell for Lab-on-Chip Devices: Applied to Nitrate Detection

Flexible Metal/Oxide/Metal Transparent Electrodes Made of Thermally Evaporated MoO3/Ag/MoO3 for Thin Film Heaters

Development of a disposable and easy-to-fabricate microfluidic PCR device for DNA amplification

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Product

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Flexible Metal/Oxide/Metal Transparent Electrodes Made of Thermally Evaporated MoO₃/Ag/MoO₃ for Thin Film Heaters