Detoxification of aflatoxin B1 by manganese peroxidase from the white-rot fungus Phanerochaete sordida YK-624

Wang, Jianqiao; Ogata, Makoto; Hirai, Hirofumi; Kawagishi, Hirokazu

doi:10.1111/j.1574-6968.2010.02158.x

Cited by 150 publications

(103 citation statements)

References 35 publications

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“…This was concluded by the application of hydrochloric acid to aflatoxin B1 contaminated corn gluten. Enzymes of diverse origins may also be a useful tool to reduce the aflatoxin contamination of different matrices, as it was suggested by Wang et al (2011). In line with these observations, microorganisms may have advantages with respect to the use of a purified enzyme, since they provide a subset of metabolic pathways that potentially could reduce the aflatoxins levels (Guan et al, 2010).…”

Section: Approaches In the Articles Regarding To Foodssupporting

confidence: 52%

The Evolutionary Dynamics in the Research on Aflatoxins During the 2001-2010 Decade

Theumer¹,

Rubinstein²

2011

Aflatoxins - Biochemistry and Molecular Biology

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Section: Approaches In the Articles Regarding To Foodssupporting

confidence: 52%

The Evolutionary Dynamics in the Research on Aflatoxins During the 2001-2010 Decade

Theumer¹,

Rubinstein²

2011

Aflatoxins - Biochemistry and Molecular Biology

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“…These compounds can have antifungal properties (60) and can be detoxified by flavonol reductases. A similar detoxification function can be attributed to several oxidoreductases, such as MnP, which is used by the whiterot fungus Phanerochaete sordida for the detoxification of Aspergillus niger mycotoxin aflatoxin B1 (61). Another group of enzymes important for detoxification processes, the glutathione S-transferases, are strongly overexpressed.…”

Section: Discussionmentioning

confidence: 99%

Differential Gene Expression in Pycnoporus coccineus during Interspecific Mycelial Interactions with Different Competitors

Arfi

Levasseur

Record

2013

Appl Environ Microbiol

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Fungi compete against each other for environmental resources. These interspecific combative interactions encompass a wide range of mechanisms. In this study, we highlight the ability of the white-rot fungus Pycnoporus coccineus to quickly overgrow or replace a wide range of competitor fungi, including the gray-mold fungus Botrytis cinerea and the brown-rot fungus Coniophora puteana. To gain a better understanding of the mechanisms deployed by P. coccineus to compete against other fungi and to assess whether common pathways are used to interact with different competitors, differential gene expression in P. coccineus during cocultivation was assessed by transcriptome sequencing and confirmed by quantitative reverse transcription-PCR analysis of a set of 15 representative genes. Compared with the pure culture, 1,343 transcripts were differentially expressed in the interaction with C. puteana and 4,253 were differentially expressed in the interaction with B. cinerea, but only 197 transcripts were overexpressed in both interactions. Overall, the results suggest that a broad array of functions is necessary for P. coccineus to replace its competitors and that different responses are elicited by the two competitors, although a portion of the mechanism is common to both. However, the functions elicited by the expression of specific transcripts appear to converge toward a limited set of roles, including detoxification of secondary metabolites. Interspecific interactions are key elements in the ecology of fungi, which live in complex communities and often have to compete against each other for a territory and the resources it contains (1, 2). Competitive mycelial interactions usually result in replacement (one of the competitors overruns the other) or deadlock (neither fungus gains any territory). The outcome of these interactions will in turn affect the succession of species, community development, and substratum decay (3-5). This ability to eliminate competitors has also been used as a biotechnological tool, with the development of methods using aggressive, strongly antagonistic species, such as Trichoderma sp., to control plantpathogenic and wood rot fungi (1, 6, 7).When antagonistic relations occur, a broad array of responses can be observed, including changes in mycelial morphology at the interaction front, modification of metabolism, and production and secretion of extracellular enzymes (1,(8)(9)(10)(11). Two main pathways are used to gain an advantage over the competitor: development of attack or defense mechanisms and improvements in nutrient uptake (12). For instance, the overproduction of a large number of oxidative enzymes, such as laccases, phenoloxidases, and peroxidases, has been demonstrated in multiple interactions (13-16). As most of these enzymes are also secreted during oxidative and abiotic stresses, it has been suggested that they are part of a defensive function that contributes to the detoxification of reactive oxygen species (ROS). Laccases and peroxidases are also thought to be involved in morpholo...

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“…Likewise halophenols [178][179][180][181][182] bisphenol A, [183][184][185] various hormones and so-called endocrine disrupting compounds [186][187][188] or even TNT [189,190] have been reported. Non-phenolic compounds may be ‗inactivated' using the LMS or PMS strategy [36,[191][192][193][194][195][196][197][198].…”

Section: Phenol Detoxificationmentioning

confidence: 99%

Enzyme Initiated Radical Polymerizations

2012

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Detoxification of aflatoxin B1 by manganese peroxidase from the white-rot fungus Phanerochaete sordida YK-624

Cited by 150 publications

References 35 publications

The Evolutionary Dynamics in the Research on Aflatoxins During the 2001-2010 Decade

The Evolutionary Dynamics in the Research on Aflatoxins During the 2001-2010 Decade

Differential Gene Expression in Pycnoporus coccineus during Interspecific Mycelial Interactions with Different Competitors

Enzyme Initiated Radical Polymerizations

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