Deuterium-free water in complex life-support systems of long-term space missions

Sinyak, Yu. V.; Grigoriev, A.I.; Gaydadimov, V.; Gurieva, T.S.; Levinskih, M.; Покровский, Б. Г.

doi:10.1016/s0094-5765(02)00013-9

Cited by 13 publications

(9 citation statements)

References 7 publications

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“…In its turn the influence of DDW on the molecular dynamics of DNA can be explained by several mechanisms. It is known, that decrease of deuterium concentration in functionally active regions of a DNA molecule may increase the rate of transcription and replication [98]. The latter effect can be caused by the influence of deuterium on the probability of occurrence of open states between complementary pairs of nitrogenous bases, which can significantly change the speed of reading genetic information.…”

Section: Discussionmentioning

confidence: 99%

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Deuterium-Depleted Water Influence on the Isotope 2H/1H Regulation in Body and Individual Adaptation

et al. 2019

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This review article presents data about the influence of deuterium-depleted water (DDW) on biological systems. It is known that the isotope abundances of natural and bottled waters are variable worldwide. That is why different drinking rations lead to changes of stable isotopes content in body water fluxes in human and animal organisms. Also, intracellular water isotope ratios in living systems depends on metabolic activity and food consumption. We found the 2H/1H gradient in human fluids (δ2H saliva >> δ2H blood plasma > δ2Hbreast milk), which decreases significantly during DDW intake. Moreover, DDW induces several important biological effects in organism (antioxidant, metabolic detoxification, anticancer, rejuvenation, behavior, etc.). Changing the isotope 2H/1H gradient from “2H blood plasma > δ2H visceral organs” to “δ2H blood plasma << δ2H visceral organs” via DDW drinking increases individual adaptation by isotopic shock. The other possible mechanisms of long-term adaptation is DDW influence on the growth rate of cells, enzyme activity and cellular energetics (e.g., stimulation of the mitochondrion activity). In addition, DDW reduces the number of single-stranded DNA breaks and modifies the miRNA profile.

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Section: Discussionmentioning

confidence: 99%

“…It is planned to use the mechanisms of radioprotective action of water with depleted concentrations of heavy stable isotopes 18 О and 2 H described above during travel by humans in outer space [98,99].…”

Section: Biological Effects Of Deuterium-depleted Water (Ddw)mentioning

confidence: 99%

Deuterium-Depleted Water Influence on the Isotope 2H/1H Regulation in Body and Individual Adaptation

et al. 2019

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“…The water vapors and collected water should be treated by methods as close to the natural treatment processes (electrostatic ionization, soil infiltration, percolation, etc.) as possible to provide its biological activity (Sinyak et al, 2003).…”

Section: Closed Water Loopmentioning

confidence: 99%

Application of space technology to the design of sustainable settlements in hot deserts: Bioregenerative life support systems

Polyakov¹,

Musaev

Polyakov³

2009

Nat Prec

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Water scarcity in hot deserts, which cover about one-fifth of the Earth's land area, along with rapid expansion of hot deserts into arable lands is one of the key global environmental problems. This paper proposes and substantiates an interdisciplinary approach to sustainable settlements in hot deserts using the accomplishments in the design of closed bioregenerative life support systems (CBLSS) for beyond-Earth (Lunar, Martian) settlements. Extensive space technology experience in the design of CBLSSes, which simultaneously produce food, water, nutrients, and fertilizers, process wastes, and revitalize air, has been analyzed and systematized with application to hot deserts, which represent extreme habitats with high input of solar energy, poor organic life, and nutrient/mineral-rich soils. A general flow diagram and design principles for hot-desert bioregenerative life support systems (BLSS), which may be considered as solarpowered "bioreactors" with accelerated cycles of carbon and nutrients, are formulated. Research and design guidelines for BLSS solar energy utilization, accelerated food production, water production and recycling, and wastes processing are suggested. Environmental and socioeconomic benefits of building hot-desert BLSSes are discussed.

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“…For example, the electrostatic treatment of water vapors can be accomplished by Chizhevsky air ionizers. The results of space technology studies demonstrating that a reduced concentration of deuterium in water can enhance the biological activity of water, which implies a higher rate of biomass growth and faster consumption of wastes, can also be utilized (19). If necessary, the collected water can be treated to a higher purity degree by the solar still integrated with the greenhouse (20).…”

Section: Monitoringmentioning

confidence: 99%

Is Sustainable Development of Deserts Feasible?

et al. 2008

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Deuterium-free water in complex life-support systems of long-term space missions

Cited by 13 publications

References 7 publications

Deuterium-Depleted Water Influence on the Isotope 2H/1H Regulation in Body and Individual Adaptation

Deuterium-Depleted Water Influence on the Isotope 2H/1H Regulation in Body and Individual Adaptation

Application of space technology to the design of sustainable settlements in hot deserts: Bioregenerative life support systems

Is Sustainable Development of Deserts Feasible?

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