Developing a supercritical fluid extraction method assisted by cold pressing for extraction of pequi (Caryocar brasiliense)

Johner, Júlio C. F.; Hatami, Tahmasb; Meireles, M. Ângela A.

doi:10.1016/j.supflu.2018.03.005

Cited by 39 publications

(24 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The medicinal parts of ginseng (roots and flower buds) are increasingly popular as dietary supplements due to the current trend towards a holistic approach to healthcare. Although numerous extraction methods exist in the typical home, including supercritical fluid, ultrasonic wave, microwave, and heat reflux (Dai and Orsat, 2010; Wang et al, 2010; Ajavakom et al, 2012; Johner et al, 2018; Zhang et al, 2018) traditional water extraction and powdering are the most frequently used methods to obtain the medicinal benefits of ginseng via ingestion (Nabavi et al, 2018; Taban and Saharkhiz, 2015). The main effective constituents of ginseng are the ginsenosides, of which Rb1, a protopanaxadiol (PPD)-type ginsenoside with a dammarane-type triterpenoid as an aglycone, is the main bioactive component (Quan et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Rb1, the Primary Active Ingredient in Panax ginseng C.A. Meyer, Exerts Antidepressant-Like Effects via the BDNF–Trkb–CREB Pathway

et al. 2019

View full text Add to dashboard Cite

Panax ginseng C.A. Meyer (Araliaceae), a popular tonic and dietetic herbal medicine, has been traditionally prescribed in China and other countries to treat affective disorders. The medicinal parts of ginseng, the roots and flower buds, have become increasingly popular as dietary supplements due to the current holistic healthcare trend. We have investigated for the first time the antidepressive actions of the different medicinal parts, namely, the main roots, fibrous roots, and flower buds (in water extract and powder), of garden-cultivated ginseng through behavioral and drug-induced tests in mice. The water extracts, but not the powders of ginseng fibrous roots, flower buds, and main roots (1.5 g of crude drug per kilogram, p.o.), significantly reduced the immobility time in the forced swim test (FST) and tail suspension test (TST); moreover, the water extracts enhanced the 5-hydroxytryptophan (5-HTP)-induced head-twitch response and antagonized the action of reserpine in the mouse. We then explored the antidepressive mechanism of action of the ginsenoside Rb1 (Rb1) related to the brain-derived neurotrophic factor (BDNF) and its downstream proteins in mice exposed to chronic unpredictable mild stress (CUMS). Treatment with Rb1 (20 mg/kg, p.o.) for 21 days significantly attenuated the CUMS-induced decrease in the activities of BDNF, tropomyosin-related kinase B (TrkB), protein kinase B (AKT), extracellular regulatory protein kinase (ERK), and cyclic adenosine monophosphate (cAMP) response element binding protein (CREB) in the mouse hippocampal CA3 region and prefrontal cortex (PFC). Interestingly, treatment with the novel TrkB antagonist ANA-12 (0.5 mg/kg, i.p.) did not alter the level of BDNF but significantly blocked the antidepressive effects of Rb1 on proteins downstream of BDNF in CUMS-treated mice. These results suggest that BDNF–TrkB–CREB signaling may be involved in the antidepressive mechanism of the action of Rb1.

show abstract

Section: Introductionmentioning

confidence: 99%

Rb1, the Primary Active Ingredient in Panax ginseng C.A. Meyer, Exerts Antidepressant-Like Effects via the BDNF–Trkb–CREB Pathway

et al. 2019

View full text Add to dashboard Cite

show abstract

“…A recent study also analyzed the possibility of combining the use of supercritical fluid extraction with cold pressing to improve the extraction of fennel by supercritical fluid extraction alone [63]. The combination of these two extraction methods was originally developed by Johner et al [64] for the extraction of pequi. This researchers demonstrated some promising results: a faster extraction rate with the consumption of less solvent.…”

Section: State-of-the-art Of Extraction Methodsmentioning

confidence: 99%

Mexican Microalgae Biodiversity and State-Of-The-Art Extraction Strategies to Meet Sustainable Circular Economy Challenges: High-Value Compounds and Their Applied Perspectives

et al. 2019

View full text Add to dashboard Cite

In recent years, the demand for naturally derived products has hiked with enormous pressure to propose or develop state-of-the-art strategies to meet sustainable circular economy challenges. Microalgae possess the flexibility to produce a variety of high-value products of industrial interests. From pigments such as phycobilins or lutein to phycotoxins and several polyunsaturated fatty acids (PUFAs), microalgae have the potential to become the primary producers for the pharmaceutical, food, and agronomical industries. Also, microalgae require minimal resources to grow due to their autotrophic nature or by consuming waste matter, while allowing for the extraction of several valuable side products such as hydrogen gas and biodiesel in a single process, following a biorefinery agenda. From a Mexican microalgae biodiversity perspective, more than 70 different local species have been characterized and isolated, whereas, only a minimal amount has been explored to produce commercially valuable products, thus ignoring their potential as a locally available resource. In this paper, we discuss the microalgae diversity present in Mexico with their current applications and potential, while expanding on their future applications in bioengineering along with other industrial sectors. In conclusion, the use of available microalgae to produce biochemically revenuable products currently represents an untapped potential that could lead to the solution of several problems through green technologies. As such, if the social, industrial and research communities collaborate to strive towards a greener economy by preserving the existing biodiversity and optimizing the use of the currently available resources, the enrichment of our society and the solution to several environmental problems could be attained.

show abstract

“…The extraction of bioactives through supercritical fluids has taken a great interest, as they have many advantages, especially due to the high extraction efficiency [56,57]. A supercritical fluid is a substance that is under operating conditions of pressure and temperature higher than its thermodynamic critical point.…”

Section: Super Critical Fluid Extraction (Sce)mentioning

confidence: 99%

Emerging strategies for the development of food industries

et al. 2019

View full text Add to dashboard Cite

Undoubtedly, the food industry is undergoing a dynamic process of transformation in its continual development in order to meet the requirements and solve the great problems represented by a constantly growing global population and food claimant in both quantity and quality. In this sense, it is necessary to evaluate the technological trends and advances that will change the landscape of the food processing industry, highlighting the latest requirements for equipment functionality. In particular, it is crucial to evaluate the influence of sustainable green biotechnology-based technologies to consolidate the food industry of the future, today, and it must be done by analyzing the mega-consumption trends that shape the future of industry, which range from local sourcing to on-the-go food, to an increase in organic foods and clean labels (understanding ingredients on food labels). While these things may seem alien to food manufacturing, they have a considerable influence on the way products are manufactured. This paper reviews in detail the conditions of the food industry, and particularly analyzes the application of emerging technologies in food preservation, extraction of bioactive compounds, bioengineering tools and other biobased strategies for the development of the food industry.

show abstract

Developing a supercritical fluid extraction method assisted by cold pressing for extraction of pequi (Caryocar brasiliense)

Cited by 39 publications

References 21 publications

Rb1, the Primary Active Ingredient in Panax ginseng C.A. Meyer, Exerts Antidepressant-Like Effects via the BDNF–Trkb–CREB Pathway

Rb1, the Primary Active Ingredient in Panax ginseng C.A. Meyer, Exerts Antidepressant-Like Effects via the BDNF–Trkb–CREB Pathway

Mexican Microalgae Biodiversity and State-Of-The-Art Extraction Strategies to Meet Sustainable Circular Economy Challenges: High-Value Compounds and Their Applied Perspectives

Emerging strategies for the development of food industries

Contact Info

Product

Resources

About