This study aims to describe the relationship between students' attitudes among persistence, creativity, and tolerance in science subjects in Muaro Jambi Middle School, Jambi City Middle School, and Batanghari Regency Middle School. The research design used was quantitative associated with a correlation design. The data collection technique used is total sampling. The research subjects were 767 students. The research instruments used were closed questionnaires consisting of 54 statements of attitude questionnaire, persistence, questionnaire of 30 statements, creativity questionnaire as many as 31 statements and tolerance questionnaires as many as 32 statements. The data analysis technique used is descriptive statistics and inferential statistics. Based on the results of the correlation test on the four variables obtained, a relationship between students' attitudes toward persistence, creativity, and tolerance in science subjects in the Middle School in Muaro Jambi Regency is with a sufficient category. Then students' attitudes toward persistence, creativity, and tolerance in science subjects in Jambi City Junior High School have a positive relationship with a strong category. Likewise, students' attitudes toward persistence, creativity, and tolerance in science subjects in the Batanghari Regency Middle School have a positive relationship with a strong category.