2020
DOI: 10.1039/d0qm00368a
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Development and advancement of rotaxane dendrimers as switchable macromolecular machines

Abstract:

Rotaxane dendrimer is a newly emerging large family of the mechanically interlocked molecules (MIMs), whereas it combines the concept of molecular switching properties into the hyperbranched dendrimers to render new...

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Cited by 25 publications
(25 citation statements)
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References 96 publications
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“…As a result, as-prepared polymer composites or other novel nanostructured magnetic composites offered potential biomedical applications in simultaneous gene delivery, imaging contrast enhancement, and mechanistic study. To achieve the next generation in vivo nano-theranostic anti-cancer drug delivery systems, more sophisticated, stimuli-responsive polymeric/dendritic nanostructures held by mechanical bonds for bio-evaluation on imaging and active drug release on demand [ 40 , 41 , 42 , 43 , 44 , 45 , 46 ] would be developed for targeting various brain tumours.…”
Section: Discussionmentioning
confidence: 99%
“…As a result, as-prepared polymer composites or other novel nanostructured magnetic composites offered potential biomedical applications in simultaneous gene delivery, imaging contrast enhancement, and mechanistic study. To achieve the next generation in vivo nano-theranostic anti-cancer drug delivery systems, more sophisticated, stimuli-responsive polymeric/dendritic nanostructures held by mechanical bonds for bio-evaluation on imaging and active drug release on demand [ 40 , 41 , 42 , 43 , 44 , 45 , 46 ] would be developed for targeting various brain tumours.…”
Section: Discussionmentioning
confidence: 99%
“…[ [52][53][54][55][56][57][58][59][60][61][62][63]65,[68][69][70][71][72]74,77,83,85,90,[92][93][94][96][97][98][102][103][104][105][109][110][111]113,115,118,120,126,131,136,142,143,150,151,[153][154][155][156][157][158]…”
Section: The Level 1 Challenge: the Characteristics Of Molecules To B...unclassified
“…Relatively, convergent approach builds the core end point starting from the peripheral groups, to form a dendron segment. During recent years, a variety of rotaxane dendrimers have been synthesized and characterized successfully [142,143,150,151,[157][158][159]162]. They have precise arrangement of rotaxane units and stimulus-response sites and functional groups.…”
Section: The Level 3 Challenge: Integrate At System Level Crossbar An...mentioning
confidence: 99%
“…Finally, one should also mention the outstanding work of Yang and co-workers on organometallic rotaxane dendrimers constructed with mechanically interlocked pillar[5]arene moieties [ 90 , 91 , 92 , 93 , 94 , 95 , 96 ]. These compounds are out of the scope of the present paper and this chemistry has been summarized in recent review articles [ 97 ].…”
Section: Self-assembled Dendrimersmentioning
confidence: 99%