Development and Characterization of a Buccoadhesive Dosage Form of Oxycodone Hydrochloride

Parodi, Brunella; Russo, Eleonora; Caviglioli, Gabriele; Cafaggi, Sergio; Bignardi, Gaetano

doi:10.3109/03639049609069353

Cited by 86 publications

(39 citation statements)

References 7 publications

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“…employed as a quality control procedure in pharmaceutical production and product development. Standard USP or BP dissolution apparatus have been used to study in vitro release profiles using both rotating elements, paddle [20,21,22] and basket. [23,24] Dissolution medium used for the study varied from 100-500 ml and speed of rotation from 50-100 rpm.…”

Section: -Drug Release Profilesmentioning

confidence: 99%

Magnetic Microspheres: A Novel Drug Delivery System

Farah¹

2017

WJPPS

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A well designed controlled drug delivery system can provide a therapeutic amount of drug to the proper site in the body and then maintain the desired drug concentration for the specific period of time.A number of approaches are available in delivering therapeutic substance to the target site in sustained and controlled release fashion.One such approach is using magnetic microspheres as carriers for drugs. Microsphere drug delivery system has gained vast attention due to its diverse applications that range from targeting the drug to specific site to imaging and helping the diagnostic features. One of its important application is that it is used for targeting tumors using anticancer drugs. Being more stable, it has an advantage over other delivery systems like liposomes. The main objectives of this review is to highlight some important aspects of magnetic microspheres as a novel drug delivery system. The review shall cover definitions, concepts, types, mechanism of targeting, evaluation and characteristics of magnetic microspheres as well as various methods and techniques used in their preparations. The review also entails various applications and future prospects of magnetic microspheres.

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Section: -Drug Release Profilesmentioning

confidence: 99%

Magnetic Microspheres: A Novel Drug Delivery System

Farah¹

2017

WJPPS

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“…In vitro drug release studies have been employed as a quality control procedure in pharmaceutical production and product development. Standard USP or BP dissolution apparatus have been used to study in vitro release profiles using both rotating elements, paddle [17][18][19][20] and basket [21,22]. Dissolution medium used for the study varied from 100-500ml and speed of rotation from 50-100rpm.…”

Section: Drug Release Profiles [16]mentioning

confidence: 99%

Magnetic Microspheres: A Novel Drug Delivery System

Farah

2016

JAPLR

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A well designed controlled drug delivery system can provide a therapeutic amount of drug to the proper site in the body and then maintain the desired drug concentration for the specific period of time. A number of approaches are available in delivering therapeutic substance to the target site in sustained and controlled release fashion. One such approach is using magnetic microspheres as carriers for drugs. Microsphere drug delivery system has gained vast attention due to its diverse applications that range from targeting the drug to specific site to imaging and helping the diagnostic features.One of its important application is that it is used for targeting tumors using anticancer drugs. Being more stable, it has an advantage over other delivery systems like liposomes. The main objectives of this review are to highlight some important aspects of magnetic microspheres as a novel drug delivery system. The review shall cover definitions, concepts, types, mechanism of targeting, evaluation and characteristics of magnetic microspheres as well as various methods and techniques used in their preparations. The review also entails various applications and future prospects of magnetic microspheres.

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“…A modified balance method (Parodi et al, 1996) was used to determine the bioadhesive performance of the ocular minitablets by measuring the force required to detach the tablets from a mucosal surface. The instrument is broadly composed of a modified two arm physical balance in which the right pan had been replaced by a glass plate (4 × 4 cm).…”

Section: Bioadhesion Potential Of Insertsmentioning

confidence: 99%