Flours processed from eight cassava roots were selected from recently developed Cassava Mosaic Disease resistant varieties (92b/00061, 95/0289, 92/0057, 96/1632, 98/0505, 97/2205, TME419 and 92/0326). They were evaluated for proximate composition, hydrogen cyanide, vitamin A and functional properties. They were also processed into noodles adapting a locally fabricated cold extruder as a single-screw extruder. The extruded cassava noodles were cooked and subjected to sensory analysis. Principal component and cluster analyses of the parameters were adopted using the correlation matrix with the objective of grouping the varieties into functional groups. The proximate composition showed that mean protein value ranged from 1.93% (98/0505) to 2.60% (96/1632) and fat ranged from 0.46% (92/0326 and 95/0289) to 0.95% (96/1632). The principal component analysis showed that PC 1 , PC 2 and PC 3 were key components contributing 90.90% of the variables. Vitamin A determined as carotenoid ranged from 1.94 (92/0057) to 2.40 µg/g (TME419) while hydrogen cyanide concentration ranged from 8.20 (92/0057) to 11.14 mg/kg (96/1632). Noodles made from 95/0289 CMD variety had the least acceptable sensory properties while those made from 98/ 0505 were most generally acceptable. No significant (P≥0.05) differences were noticed in taste, colour and general acceptability of all the samples. The sensory evaluation of noodles made from the eight cassava varieties (colour, taste, flavour, texture and general acceptability) produced two principal components which accounted for 85.80% while the functional properties explained 81.30% of the variations. The key sensory properties with significant eigenvalues based on their loadings (≥0.5) were colour, taste, texture and general acceptability. Compared to raw samples, dried noodles were about 1.98 times, while cooked noodles were up to three times greater in diameter, respectively. The result showed that cassava flour could serve as a good substitute to wheat flour in noodle production and utilisation.