2010
DOI: 10.37285/ijpsn.2010.3.3.10
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Development and Evaluation of Guaifenesin Bilayer Tablet

Abstract: The objective of the present research was to develop a Bilayer tablet of guaifenesin (GBT) using superdisintegrant MCC and sodium starch glycolate for the fast release layer and metalose 90 SH and carbopol 934 for the sustaining layer. The guaifenesin SR granules of different formulation were evaluated for bulk density, tapped density, angle of repose, Carr’s index and Hausners ratio and results were found to be 0.460 ± 0.12 to 0.515 ± 0.03 gm/cm3 , 0.550 ±0.03 to 0.590 ±0.04 gm/cm3 , 19 ±0.01 to 26 ± 0.23, 13… Show more

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“…Hypertension, or high blood pressure, is a major public health concern around the world because of its large contribution to the global health burden 1 and its function as a major risk factor for a variety of disease processes. In the year 2019, high blood pressure was responsible for 54% of strokes, 47% of ischemic heart disease, 75% of hypertensive disease, and 25% of all cardiovascular disease worldwide.…”
Section: Introductionmentioning
confidence: 99%
“…Hypertension, or high blood pressure, is a major public health concern around the world because of its large contribution to the global health burden 1 and its function as a major risk factor for a variety of disease processes. In the year 2019, high blood pressure was responsible for 54% of strokes, 47% of ischemic heart disease, 75% of hypertensive disease, and 25% of all cardiovascular disease worldwide.…”
Section: Introductionmentioning
confidence: 99%